Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.47 |
| ▸ | KIF11 | P52732 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | DUT | P33316 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264150 | 0.93 | KCNN4 (0.50) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL4254994 | 0.86 | KCNN4 (0.44) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL12264133 | 0.80 | KIF11 (0.68) | KCNN4KIF11DUTTSHRMAPT | |
| SCHEMBL14156837 | 0.80 | HTR2A (0.40) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL2223266 | 0.79 | KCNN4 (0.44) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL17929547 | 0.79 | KIF11 (0.57) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL17426858 | 0.79 | KIF11 (0.36) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL14156834 | 0.76 | KIF11 (0.36) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL191706 | 0.76 | KCNN4 (0.52) | KCNN4KIF11HTR2AHTR2COPRK1 | |
| SCHEMBL29262767 | 0.76 | KCNN4 (0.61) | KCNN4KIF11HTR2AHTR2COPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026263-B2 | Methods for inhibiting neoproliferative changes in blood vessel walls | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-09-27 | — | — | US | disclosed |
| US-8026263-B2 | Methods for inhibiting neoproliferative changes in blood vessel walls | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-09-27 | — | — | US | disclosed |
| US-7235577-B1 | Non-peptide inhibition of T-lymphocyte activation and therapies related thereto | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-26 | — | — | US | disclosed |
| US-7235577-B1 | Non-peptide inhibition of T-lymphocyte activation and therapies related thereto | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-26 | — | — | US | disclosed |