Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264150 | 0.82 | KCNN4 (0.50) | KCNN4KIF11ADRA1AHTR2AHTR2C | |
| SCHEMBL4199968 | 0.82 | KCNN4 (0.56) | KCNN4KIF11KMT2AAKR1B1CYP2C19 | |
| SCHEMBL12264151 | 0.79 | KCNN4 (0.47) | KCNN4KIF11ADRA1AHTR2AHTR2C | |
| SCHEMBL191706 | 0.77 | KCNN4 (0.52) | KCNN4KIF11ADRA1AHTR2AHTR2C | |
| SCHEMBL4254994 | 0.77 | KCNN4 (0.44) | KCNN4KIF11ADRA1AHTR2AHTR2C | |
| SCHEMBL2390487 | 0.77 | KCNN4 (0.44) | KCNN4KIF11ADRA1AHTR2AHTR2C | |
| SCHEMBL2392958 | 0.77 | KCNN4 (0.49) | KCNN4KIF11ADRA1AHTR2AHTR2C | |
| SCHEMBL14156837 | 0.74 | HTR2A (0.40) | KCNN4KIF11ADRA1AHTR2AHTR2C | |
| SCHEMBL2273209 | 0.73 | KCNN4 (0.57) | KCNN4KIF11ADRA1AHTR2AHTR2C | |
| SCHEMBL29262767 | 0.73 | KCNN4 (0.61) | KCNN4KIF11ADRA1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011086553-A1 | CYCLIC PEPTIDES, COMPOSITIONS COMPRISING THEM AND USES THEREOF AS NUCLEASES OF NUCLEOTIDIC MACROMOLECULES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2011-07-21 | — | — | WO | disclosed |