Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 6/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10479267 | 0.99 | NAMPT (0.45) | NAMPTASAH1EPHX1LMNACYP3A4 | |
| SCHEMBL28061960 | 0.72 | — | — | |
| SCHEMBL28323379 | 0.71 | — | — | |
| SCHEMBL27860620 | 0.70 | PKM (0.35) | CYP3A4SMN1; SMN2 | |
| SCHEMBL27847236 | 0.70 | KDM4E (0.45) | ASAH1 | |
| SCHEMBL10377419 | 0.68 | ALDH1A1 (0.38) | — | |
| SCHEMBL27674320 | 0.67 | — | — | |
| SCHEMBL28312655 | 0.66 | — | — | |
| SCHEMBL24176160 | 0.65 | TDP1 (0.65) | NAMPTEPHX1 | |
| SCHEMBL10739485 | 0.65 | TDP1 (0.65) | NAMPTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011017545-A1 | N1-SUBSTITUTED-5-FLUORO-2-OXOPYRIMIDINONE-1(2H)-CARBOXAMIDE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |