SCHEMBL1226540

SCHEMBL1226540

OC(COc1ccc(C2(c3ccc(OCC(O)CC4CO4)cc3)c3ccccc3-c3ccccc32)cc1)CC1CO1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RRM1 P23921 1/20 0.38
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 2/20 0.37
OPRK1 P41145 1/20 0.37
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
HTT P42858 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PKM P14618 1/20 0.34
POLB P06746 1/20 0.34
PDK2 Q15119 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108679 0.89 TDP1 (0.48) RRM1KMT2AMEN1SMN1; SMN2MAPT
SCHEMBL21829155 0.87 TDP1 (0.40) RRM1KMT2AMEN1SMN1; SMN2MAPT
SCHEMBL23588576 0.86 TDP1 (0.45) RRM1KMT2AMEN1SMN1; SMN2MAPT
SCHEMBL13735294 0.85 TDP1 (0.44) RRM1KMT2AMEN1SMN1; SMN2MAPT
SCHEMBL13827161 0.85 TDP1 (0.44) RRM1KMT2AMEN1SMN1; SMN2MAPT
SCHEMBL13735291 0.85 TDP1 (0.44) RRM1KMT2AMEN1SMN1; SMN2MAPT
SCHEMBL10049666 0.82 TDP1 (0.41) KMT2AMEN1SMN1; SMN2MAPTKDM4E
SCHEMBL28432410 0.82 BACE1 (0.44) RRM1KMT2AMEN1SMN1; SMN2MAPT
SCHEMBL10049652 0.82 TDP1 (0.40) KMT2AMEN1SMN1; SMN2MAPTKDM4E
SCHEMBL25912924 0.82 TDP1 (0.40) KMT2AMEN1SMN1; SMN2MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2019-06-06 US disclosed
EP-2668156-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2013-12-04 EP disclosed
US-8586268-B2 Oxime ester photoinitiators BASF SE (DE) 2013-11-19 US disclosed
EP-2303833-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2013-10-16 EP disclosed
WO-2012101245-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2012-08-02 WO disclosed
EP-2303833-A2 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2011-04-06 EP disclosed
EP-2285836-A1 PHOTOINITIATOR MIXTURES BASF SE (DE) 2011-02-23 EP disclosed
US-20100188765-A1 Oxime Ester Photoinitiators CIBA CORPORATION 2010-07-29 US disclosed
EP-2144876-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2010-01-20 EP disclosed
EP-2144894-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2010-01-20 EP disclosed
WO-2008138724-A1 OXIME ESTER PHOTOINITIATORS BASF SE (CH) 2008-11-20 WO disclosed
EP-1963374-A1 OXIME ESTER PHOTOINITIATORS Ciba Holding Inc. (CH) 2008-09-03 EP disclosed
EP-1957457-A1 OXIME ESTER PHOTOINITIATORS Ciba Holding Inc. (CH) 2008-08-20 EP disclosed
US-20080096115-A1 Oxime Ester Photoinitiators CIBA SPECIALTY CHEMICALS CORP. 2008-04-24 US disclosed
WO-2007071497-A1 OXIME ESTER PHOTOINITIATORS CIBA HOLDING INC. (CH) 2007-06-28 WO disclosed
WO-2007062963-A1 OXIME ESTER PHOTOINITIATORS CIBA HOLDING INC. (CH) 2007-06-07 WO disclosed
EP-1778636-A1 OXIME ESTER PHOTOINITIATORS Ciba SC Holding AG (CH) 2007-05-02 EP disclosed
WO-2006018405-A1 OXIME ESTER PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-02-23 WO disclosed
EP-1567518-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS Ciba SC Holding AG (CH) 2005-08-31 EP disclosed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080096115-A1 Oxime Ester Photoinitiators NR2E3, CBR3, AHR RRM1 660/4885KMT2A 2146/4885MEN1 3961/4885
US-20100188765-A1 Oxime Ester Photoinitiators NR2E3, CYP3A4, CHRM4 RRM1 494/4885KMT2A 1176/4885MEN1 3989/4885
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT SULT1E1, COX6B1, SULT1A1 RRM1 1879/4885KMT2A 930/4885MEN1 4751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.