SCHEMBL12268596

SCHEMBL12268596

c1ccc(-c2ccc(-c3ccc4c(c3)c3ccccc3n4-c3cccc(-c4cnc5c6ccccc6c6ccccc6c5n4)c3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSPO P30536 1/20 0.34
PTGER4 P35408 1/20 0.33
PDE10A Q9Y233 1/20 0.33
NPY5R Q15761 1/20 0.32
DHFR P00374 1/20 0.32
NR3C1 P04150 1/20 0.32
MAPT P10636 2/20 0.32
NPC1 O15118 1/20 0.32
PDGFRB P09619 1/20 0.32
KDR P35968 1/20 0.32
FLT3 P36888 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ASIC3 Q9UHC3 1/20 0.31
PIK3CA P42336 1/20 0.31
PIK3CB P42338 1/20 0.31
PIK3CG P48736 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12268606 1.00 KDM4E (0.38) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL17464157 0.99 KDM4E (0.40) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL17464150 0.99 KDM4E (0.40) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL18777987 0.99 KDM4E (0.37) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL18777869 0.99 KDM4E (0.37) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL17464143 0.98 KDM4E (0.39) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL17456845 0.98 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL30150727 0.98 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL2406245 0.98 PDE10A (0.34) KDM4EATML3MBTL1PDE10ADHFR
SCHEMBL12268510 0.98 PDE10A (0.34) KDM4EATML3MBTL1PDE10ADHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10224490-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-05 US disclosed
US-20180130958-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130958-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-10 US disclosed
US-9899608-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-20 US disclosed
US-9899608-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-20 US disclosed
EP-2363398-B1 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2017-10-18 EP disclosed
US-20150318493-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, And Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-05 US disclosed
US-20150318493-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, And Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-05 US disclosed
US-9079879-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-07-14 US disclosed
US-9079879-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-07-14 US disclosed
US-20130060033-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, LIGHTING DEVICE, AND HETEROCYCLIC COMPOUND SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-07 US disclosed
US-20130060033-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, LIGHTING DEVICE, AND HETEROCYCLIC COMPOUND SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-07 US disclosed
EP-2363398-A1 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-09-07 EP disclosed
US-20110210316-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-09-01 US disclosed
US-20110210316-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110210316-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NQO1, DDT, CYP1A1 KDM4E 2976/4885ATM 4455/4885L3MBTL1 833/4885
US-20180130958-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NQO1, DDT, CYP1A1 KDM4E 2976/4885ATM 4455/4885L3MBTL1 833/4885
US-10224490-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device NQO1, DDT, CYP1A1 KDM4E 2976/4885ATM 4455/4885L3MBTL1 833/4885
US-20130060033-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, LIGHTING DEVICE, AND HETEROCYCLIC COMPOUND TRPA1, SUN2, CYBA KDM4E 3120/4885ATM 3897/4885L3MBTL1 1944/4885
US-20150318493-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, And Lighting Device NQO1, DDT, CYP1A1 KDM4E 2976/4885ATM 4455/4885L3MBTL1 833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.