SCHEMBL12268609

SCHEMBL12268609

Cc1nc2c3ccccc3c3ccccc3c2nc1-c1ccc(-c2cccc3c2oc2ccccc23)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.48
▸ PRKDC P78527 2/20 0.39
▸ MEN1 O00255 4/20 0.38
▸ KMT2A Q03164 4/20 0.38
▸ ALDH1A1 P00352 3/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ PIK3CD O00329 1/20 0.37
▸ PIK3CB P42338 1/20 0.37
▸ GGPS1 O95749 1/20 0.37
▸ TSHR P16473 2/20 0.36
▸ MAPT P10636 2/20 0.35
▸ CSF1R P07333 1/20 0.35
▸ PDGFRB P09619 1/20 0.35
▸ KIT P10721 1/20 0.35
▸ FLT3 P36888 1/20 0.35
▸ HDAC6 Q9UBN7 1/20 0.35
▸ MAPK1 P28482 2/20 0.35
▸ LMNA P02545 2/20 0.35
▸ HRH4 Q9H3N8 1/20 0.35
▸ GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18777699 0.94 ALOX5 (0.46) ALOX5PRKDCMEN1KMT2AALDH1A1
SCHEMBL18777657 0.92 ALOX5 (0.46) ALOX5PRKDCMEN1KMT2AALDH1A1
SCHEMBL18777678 0.92 ALOX5 (0.46) ALOX5PRKDCMEN1KMT2AALDH1A1
SCHEMBL14826933 0.91 ALOX5 (0.47) ALOX5PRKDCMEN1KMT2AALDH1A1
SCHEMBL12268381 0.90 ALOX5 (0.49) ALOX5PRKDCMEN1KMT2AALDH1A1
SCHEMBL18777725 0.89 ALOX5 (0.49) ALOX5PRKDCMEN1KMT2AALDH1A1
SCHEMBL18777770 0.89 ALOX5 (0.48) ALOX5PRKDCMEN1KMT2AALDH1A1
SCHEMBL12268688 0.88 ALOX5 (0.51) ALOX5PRKDCMEN1KMT2AALDH1A1
SCHEMBL12268567 0.87 ALOX5 (0.45) ALOX5PRKDCMEN1KMT2AALDH1A1
SCHEMBL14826943 0.86 ALOX5 (0.44) ALOX5PRKDCMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10224490-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-05 — — US disclosed
US-20180130958-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-10 — — US disclosed
US-20180130958-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-10 — — US disclosed
US-9899608-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-20 — — US disclosed
US-9899608-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-02-20 — — US disclosed
EP-2363398-B1 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2017-10-18 — — EP disclosed
US-20150318493-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, And Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-05 — — US disclosed
US-20150318493-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, And Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-05 — — US disclosed
US-9079879-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-07-14 — — US disclosed
US-9079879-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-07-14 — — US disclosed
US-20110210316-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-09-01 — — US disclosed
US-20110210316-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-09-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110210316-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NQO1, DDT, CYP1A1 ALOX5 637/4885PRKDC 4728/4885MEN1 546/4885
US-20180130958-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NQO1, DDT, CYP1A1 ALOX5 637/4885PRKDC 4728/4885MEN1 546/4885
US-10224490-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device NQO1, DDT, CYP1A1 ALOX5 637/4885PRKDC 4728/4885MEN1 546/4885
US-20150318493-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, And Lighting Device NQO1, DDT, CYP1A1 ALOX5 637/4885PRKDC 4728/4885MEN1 546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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