SCHEMBL18777699

SCHEMBL18777699

Cc1nc2c3ccccc3c3ccccc3c2nc1-c1ccc(-c2cccc(-c3ccc(-c4cccc5c4oc4ccccc45)cc3)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.46
▸ GGPS1 O95749 1/20 0.38
▸ PRKDC P78527 3/20 0.38
▸ PLA2G2A P14555 1/20 0.36
▸ PLA2G4A P47712 1/20 0.36
▸ PTGES2 Q9H7Z7 1/20 0.36
▸ PIM1 P11309 1/20 0.35
▸ CSNK2A2 P19784 1/20 0.35
▸ CSNK2B P67870 1/20 0.35
▸ PIM3 Q86V86 1/20 0.35
▸ PIM2 Q9P1W9 1/20 0.35
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ CSF1R P07333 1/20 0.34
▸ PDGFRB P09619 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ KIT P10721 1/20 0.34
▸ FLT3 P36888 1/20 0.34
▸ HDAC6 Q9UBN7 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18777678 0.98 ALOX5 (0.46) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL18777657 0.98 ALOX5 (0.46) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL18777725 0.95 ALOX5 (0.49) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL12268609 0.94 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2MEN1
SCHEMBL18777770 0.93 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2MEN1
SCHEMBL12268381 0.92 ALOX5 (0.49) ALOX5GGPS1PRKDCPTGES2MEN1
SCHEMBL14826933 0.91 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2MEN1
SCHEMBL18777611 0.91 ALOX5 (0.50) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL18777689 0.90 ALOX5 (0.49) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL18777642 0.90 ALOX5 (0.49) ALOX5GGPS1PRKDCPLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11522138-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2022-12-06 — — US disclosed
WO-2017068457-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-27 — — WO disclosed
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-27 — — US disclosed
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device RECQL, HSF1, DDX41 ALOX5 1090/4885GGPS1 797/4885PRKDC 4383/4885
US-11522138-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device RECQL, HSF1, DDX41 ALOX5 1090/4885GGPS1 797/4885PRKDC 4383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback