Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 13/20 | 0.67 |
| ▸ | AR | P10275 | 3/20 | 0.67 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | IL6 | P05231 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12272362 | 1.00 | NR3C1 (0.67) | NR3C1ARKDM1AIL6ALDH1A1 | |
| SCHEMBL12272067 | 1.00 | NR3C1 (0.67) | NR3C1ARKDM1AIL6ALDH1A1 | |
| SCHEMBL12272191 | 1.00 | NR3C1 (0.67) | NR3C1ARKDM1AIL6ALDH1A1 | |
| SCHEMBL13494367 | 0.94 | NR3C1 (0.77) | NR3C1ARKDM1AIL6ALDH1A1 | |
| SCHEMBL16252266 | 0.94 | NR3C1 (0.77) | NR3C1ARKDM1AIL6ALDH1A1 | |
| SCHEMBL12271690 | 0.94 | NR3C1 (0.77) | NR3C1ARKDM1AIL6ALDH1A1 | |
| SCHEMBL1571729 | 0.94 | NR3C1 (0.77) | NR3C1ARKDM1AIL6ALDH1A1 | |
| SCHEMBL12271720 | 0.89 | NR3C1 (0.62) | NR3C1ARKDM1AIL6MEN1 | |
| SCHEMBL12271823 | 0.89 | NR3C1 (0.62) | NR3C1ARKDM1AIL6MEN1 | |
| SCHEMBL12272688 | 0.89 | NR3C1 (0.62) | NR3C1ARKDM1AIL6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120238549-A1 | Nuclear Hormone Receptor Modulators | ABBOTT LABORATORIES (US) | 2012-09-20 | — | — | US | claimed |
| US-20120238549-A1 | Nuclear Hormone Receptor Modulators | ABBOTT LABORATORIES (US) | 2012-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238549-A1 | Nuclear Hormone Receptor Modulators | NR5A1, NR5A2, NR3C2 | NR3C1 7/4885AR 14/4885KDM1A 3323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.