SCHEMBL122735

SCHEMBL122735

CC(=Cc1c(Br)cc(Br)cc1Br)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.45
AKR1C4 P17516 1/20 0.39
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
HSD17B10 Q99714 1/20 0.39
APEX1 P27695 10/20 0.39
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ERN1 O75460 1/20 0.35
MAOB P27338 1/20 0.34
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122734 1.00 AKR1C3 (0.45) AKR1C3AKR1C4AKR1C2AKR1C1HSD17B10
SCHEMBL3069068 0.80 AKR1C3 (0.42) AKR1C3APEX1TDP1LMNA
SCHEMBL4498131 0.80 AKR1C3 (0.42) AKR1C3APEX1LMNAMAPT
SCHEMBL3069073 0.80 AKR1C3 (0.42) AKR1C3APEX1TDP1LMNA
SCHEMBL7076351 0.79 AKR1C3 (0.55) AKR1C3APEX1MAOB
SCHEMBL1490649 0.79 AKR1C3 (0.41) AKR1C3AKR1C4AKR1C2AKR1C1HSD17B10
SCHEMBL124742 0.75 AKR1C3 (0.48) AKR1C3APEX1
SCHEMBL124743 0.75 AKR1C3 (0.48) AKR1C3APEX1
SCHEMBL1490662 0.75 AKR1C3 (0.46) AKR1C3APEX1CYP3A4ERN1
SCHEMBL1804530 0.73 THRA (0.47) CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3256850-B1 HYDROGEL PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME SLINGSHOT BIOSCIENCES INC (US) 2025-07-09 EP claimed
EP-1928395-B1 DENTAL MATERIAL GDF GES FÜR DENTALE FORSCHUNG UND INNOVAT (DE) 2015-03-11 EP claimed
EP-2223957-B1 Transparent composite compound KOREA ADVANCED INST SCI & TECH (KR) 2013-06-26 EP claimed
EP-1802726-B1 PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF ADVANCED POLYMERIK PTY LTD (AU) 2011-11-30 EP claimed
US-20090298966-A1 DENTAL MATERIAL GDF GESELLSCHAFT FUR DENTALE FORSCHUNG UND INNOVATIONEN GMBH (DE) 2009-12-03 US claimed
EP-1928395-A1 DENTAL MATERIAL GDF GESELLSCHAFT FÜR DENTALE FORSCHUNG UND INNOVAT (DE) 2008-06-11 EP claimed
WO-2007034258-A1 DENTAL MATERIAL GDF Gesellschaft für Dentale Forschung und Innovationen GmbH (DE) 2007-03-29 WO claimed
US-6051733-A Sulfur-containing compounds for optical grade polymeric casting compositions UCB, S.A. (BE) 2000-04-18 US claimed
EP-0841380-B1 Method of making polymeric binders and use thereof in antifouling paints WITCO GMBH (DE) 1999-08-25 EP claimed
EP-0841380-A1 Method of making polymeric binders and use thereof in antifouling paints Witco GmbH (DE) 1998-05-13 EP claimed
EP-0483717-B1 Polymer blends KURARAY CO (JP) 1996-07-31 EP claimed
EP-0441383-B1 Use of a copolymer for the making of contact lenses MITSUBISHI RAYON CO (JP) 1996-05-08 EP claimed
JP-52138586-A None JP disclosed
EP-3997163-B1 FILLER FOR 3D PRINTING QUARZWERKE GMBH (DE) 2023-09-06 EP disclosed
EP-4224245-A1 SPECTACLE LENS Hoya Lens Thailand Ltd. (TH) 2023-08-09 EP disclosed
EP-4224244-A1 EYEGLASS LENS Hoya Lens Thailand Ltd. (TH) 2023-08-09 EP disclosed
WO-1996041842-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN A/S (NO) 1996-12-27 WO disclosed
EP-0017151-B1 COLD CURING MATERIALS FOR DENTAL PURPOSES WITH POLYMERISATION-ACTIVE SULFONES BAYER AG (DE) 1984-02-15 EP disclosed
EP-0017151-A2 Cold curing materials for dental purposes with polymerisation-active sulfones BAYER AG (DE) 1980-10-15 EP disclosed
JP-S52138586-A ANAEROBIC COMPOSITIONS HAVING IMPROVED BREAKING TORQUE STRENGTH TOAGOSEI CHEM IND CO LTD 1977-11-18 JP disclosed