SCHEMBL1490649

SCHEMBL1490649

CC(=Cc1cc(Br)cc(Br)c1Br)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.41
ERN1 O75460 1/20 0.40
EIF2AK2 P19525 1/20 0.37
CSNK2A2 P19784 1/20 0.37
CSNK2B P67870 1/20 0.37
CSNK2A1 P68400 1/20 0.37
AKR1C4 P17516 1/20 0.36
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36
HSD17B10 Q99714 1/20 0.36
APEX1 P27695 6/20 0.36
MAPT P10636 3/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
KDM4E B2RXH2 2/20 0.34
PLA2G1B P04054 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9631284 0.83 EIF2AK2 (0.55) AKR1C3EIF2AK2CSNK2A2CSNK2BCSNK2A1
SCHEMBL122734 0.79 AKR1C3 (0.45) AKR1C3ERN1AKR1C4AKR1C2AKR1C1
SCHEMBL122735 0.79 AKR1C3 (0.45) AKR1C3ERN1AKR1C4AKR1C2AKR1C1
SCHEMBL1490662 0.78 AKR1C3 (0.46) AKR1C3ERN1APEX1ALDH1A1HSP90AA1
SCHEMBL2459389 0.76 EGFR (0.49) ALDH1A1HPGDKDM4EKMT2ALMNA
SCHEMBL14689361 0.76 EGFR (0.49) ALDH1A1HPGDKDM4EKMT2ALMNA
SCHEMBL3958047 0.72 AKR1C3 (0.47) AKR1C3EIF2AK2CSNK2A2CSNK2BCSNK2A1
SCHEMBL3958052 0.72 AKR1C3 (0.47) AKR1C3EIF2AK2CSNK2A2CSNK2BCSNK2A1
SCHEMBL2489064 0.71 AKR1C3 (0.50) AKR1C3APEX1
SCHEMBL14348327 0.70 AKR1C3 (0.41) AKR1C3APEX1MAPTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8778484-B2 Laminated polyester film and antireflection film TORAY INDUSTRIES, INC. (JP) 2014-07-15 US disclosed
US-20110070416-A1 LAMINATED POLYESTER FILM AND ANTIREFLECTION FILM TORAY INDUSTRIES, INC. (JP) 2011-03-24 US disclosed
US-20100021731-A1 MULTILAYER FILM FOR USE IN PRISM SHEET, METHOD FOR PRODUCING THE SAME, PRISM SHEET AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-01-28 US disclosed