Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12806748 | 0.80 | ALOX15 (1.00) | ALOX15MAPK1HSD17B10TP53KDM4E | |
| SCHEMBL239535 | 0.75 | MAPK1 (0.62) | ALOX15MAPK1HSD17B10TP53KDM4E | |
| SCHEMBL19319842 | 0.74 | ALOX15 (0.68) | ALOX15MAPK1HSD17B10TP53KDM4E | |
| SCHEMBL10099699 | 0.74 | KDM4E (1.00) | ALOX15HSD17B10KDM4ENPC1GAA | |
| SCHEMBL28474142 | 0.73 | ALOX15 (0.57) | ALOX15MAPK1HSD17B10TP53MCL1 | |
| SCHEMBL18279960 | 0.72 | ALOX15 (0.56) | ALOX15MAPK1HSD17B10TP53KDM4E | |
| SCHEMBL29696887 | 0.71 | ALOX15 (0.55) | ALOX15MAPK1HSD17B10TP53KDM4E | |
| SCHEMBL4302091 | 0.71 | ALOX15 (0.55) | ALOX15MAPK1HSD17B10TP53KDM4E | |
| SCHEMBL15473257 | 0.71 | ALOX15 (0.55) | ALOX15MAPK1HSD17B10TP53KDM4E | |
| SCHEMBL12968466 | 0.70 | ALOX15 (0.53) | ALOX15MAPK1HSD17B10TP53MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120239140-A1 | MEDICAL PRODUCT COMPRISING AN ACTIVE COATING | BIOTRONIK AG (CH) | 2012-09-20 | — | — | US | disclosed |