SCHEMBL4302091

SCHEMBL4302091

FC(F)(F)c1cc(-c2ccccn2)n[nH]1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.55
TP53 P04637 4/20 0.55
HSD17B10 Q99714 4/20 0.55
MAPK1 P28482 4/20 0.55
SMN1; SMN2 Q16637 4/20 0.51
PIN1 Q13526 1/20 0.51
LMNA P02545 4/20 0.48
KDM4E B2RXH2 3/20 0.48
CCR1 P32246 3/20 0.48
CCR5 P51681 3/20 0.48
CCR8 P51685 3/20 0.48
POLB P06746 2/20 0.48
CYP1A2 P05177 1/20 0.48
METAP1 P53582 1/20 0.48
BLM P54132 1/20 0.48
HIF1A Q16665 1/20 0.48
DOHH Q9BU89 1/20 0.48
P4HTM Q9NXG6 1/20 0.48
RAD51 Q06609 1/20 0.48
HPGD P15428 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29696887 1.00 ALOX15 (0.55) ALOX15TP53HSD17B10MAPK1SMN1; SMN2
SCHEMBL20531019 0.94 ALOX15 (0.55) ALOX15TP53HSD17B10MAPK1SMN1; SMN2
SCHEMBL28474142 0.84 ALOX15 (0.57) ALOX15TP53HSD17B10MAPK1SMN1; SMN2
SCHEMBL28480047 0.83 PIN1 (0.51) ALOX15TP53HSD17B10MAPK1SMN1; SMN2
SCHEMBL18279960 0.80 ALOX15 (0.56) ALOX15TP53HSD17B10MAPK1SMN1; SMN2
SCHEMBL239535 0.77 MAPK1 (0.62) ALOX15TP53HSD17B10MAPK1SMN1; SMN2
SCHEMBL1528433 0.74 PIN1 (0.57) ALOX15TP53HSD17B10MAPK1SMN1; SMN2
SCHEMBL29376325 0.74 PIN1 (0.57) ALOX15TP53HSD17B10MAPK1SMN1; SMN2
SCHEMBL21192527 0.73 MAPK1 (0.45) ALOX15TP53HSD17B10MAPK1SMN1; SMN2
SCHEMBL1593197 0.73 PIN1 (0.56) ALOX15TP53HSD17B10MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104877673-A Pyridine pyrazole dinuclear copper [1] complex luminescent material and preparation method UNIV JIANGXI SCI & TECHNOLOGY 2015-09-02 CN claimed
US-20240292734-A1 Organic electroluminescent device UNITED STATES DEPARTMENT OF ENERGY 2024-08-29 US disclosed
CN-112397663-B Organic electroluminescent device 密西根大学董事会 2024-06-07 CN disclosed
US-11985888-B2 Organic electroluminescent device THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-05-14 US disclosed
CN-111961078-B Preparation method of trifluoromethyl pyridine pyrazole copper [ I ] dinuclear complex stimulus response luminescent and photochromic material 江西理工大学 2022-06-10 CN disclosed
CN-112397663-A Organic electroluminescent device 密西根大学董事会 2021-02-23 CN disclosed
US-20210050531-A1 ORGANIC ELECTROLUMINESCENT DEVICE THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2021-02-18 US disclosed
CN-111961078-A Preparation method of trifluoromethyl pyridine pyrazole copper [ I ] dinuclear complex stimulus response luminescent and photochromic material 江西理工大学 2020-11-20 CN disclosed
CN-106349259-A Organic vapor luminescent off-color material of pyridine pyrazole copper [I] complex and preparation method thereof 江西理工大学 2017-01-25 CN disclosed
CN-104877673-A Pyridine pyrazole dinuclear copper [1] complex luminescent material and preparation method UNIV JIANGXI SCI & TECHNOLOGY 2015-09-02 CN disclosed
CN-104877673-A Pyridine pyrazole dinuclear copper [1] complex luminescent material and preparation method UNIV JIANGXI SCI & TECHNOLOGY 2015-09-02 CN disclosed
US-7473477-B2 Phosphorescent iridium complexes EASTMAN KODAK COMPANY (US) 2009-01-06 US disclosed
US-20060228578-A1 Phosphorescent iridium complexes EASTMAN KODAK COMPANY 2006-10-12 US disclosed