Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 4/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.32 |
| ▸ | BCR | P11274 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9946022 | 0.91 | CA2 (0.39) | ESR1CA1CA2MGLLTP53 | |
| SCHEMBL12282435 | 0.91 | CA2 (0.39) | ESR1CA1CA2MGLLTP53 | |
| SCHEMBL14379316 | 0.87 | MEN1 (0.48) | ESR1CA1CA2MGLLABL1 | |
| SCHEMBL12281931 | 0.80 | CA2 (0.35) | CA1CA2 | |
| SCHEMBL14379330 | 0.75 | — | — | |
| SCHEMBL15462589 | 0.74 | CA1 (0.30) | CA1CA2MGLL | |
| SCHEMBL15459224 | 0.72 | CA2 (0.54) | ESR1CA1CA2MGLL | |
| SCHEMBL14379318 | 0.72 | PTGS2 (0.40) | CA1CA2MGLLABL1ABCB1 | |
| SCHEMBL806612 | 0.71 | CA2 (0.67) | ESR1CA1CA2MGLL | |
| SCHEMBL15459213 | 0.70 | ESR1 (0.36) | ESR1CA1CA2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140148596-A1 | Covalent Organic Frameworks and Methods of Making Same | CORNELL UNIVERSITY (US) | 2014-05-29 | — | — | US | disclosed |
| US-20140148596-A1 | Covalent Organic Frameworks and Methods of Making Same | CORNELL UNIVERSITY (US) | 2014-05-29 | — | — | US | disclosed |
| WO-2011127301-A2 | COVALENT ORGANIC FRAMEWORKS AND METHODS OF MAKING SAME | CORNELL UNIVERSITY (US) | 2011-10-13 | — | — | WO | disclosed |
| US-7279603-B2 | Boron and aluminum compounds in electronic components | MERCK PATENT GMBH (DE) | 2007-10-09 | — | — | US | disclosed |