Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | STAT6 | P42226 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ADK | P55263 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16330665 | 0.91 | HIF1A (0.58) | TP53STAT6HIF1AADKNPC1 | |
| SCHEMBL12284106 | 0.87 | HIF1A (0.62) | HIF1AADKPAX8TMEM97OPRK1 | |
| SCHEMBL16330689 | 0.83 | ADK (0.72) | TP53STAT6HIF1AADKNPC1 | |
| SCHEMBL16330725 | 0.82 | HIF1A (0.56) | TP53STAT6HIF1AADKNPC1 | |
| SCHEMBL16330684 | 0.82 | HIF1A (0.56) | TP53STAT6HIF1AADKNPC1 | |
| SCHEMBL16330762 | 0.82 | HIF1A (0.48) | TP53STAT6HIF1AADKNPC1 | |
| SCHEMBL26031534 | 0.82 | HIF1A (0.80) | TP53STAT6HIF1AADKNPC1 | |
| SCHEMBL16330667 | 0.81 | TP53 (0.55) | TP53STAT6HIF1AADKNPC1 | |
| SCHEMBL16330692 | 0.80 | HIF1A (0.54) | TP53STAT6HIF1AADKNPC1 | |
| SCHEMBL23723168 | 0.78 | HIF1A (0.63) | TP53STAT6HIF1AADKNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130599-A1 | POLYMERIC CONJUGATES OF ADENINE NUCLEOSIDE ANALOGS | ENZON PHARMACEUTICALS, INC. (US) | 2011-10-20 | — | — | WO | disclosed |