Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229035 | 0.92 | GAA (0.41) | GAACCR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1229039 | 0.91 | CCR1 (0.44) | GAACCR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1227001 | 0.90 | GAA (0.42) | GAACCR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1227013 | 0.90 | CCR1 (0.46) | GAACCR1POLBIRAK4ALDH1A1 | |
| SCHEMBL1228543 | 0.87 | CCR1 (0.48) | GAACCR1POLBTSHRIRAK4 | |
| SCHEMBL1227053 | 0.86 | GAA (0.44) | GAACCR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8514488 | 0.86 | CCR1 (0.42) | GAACCR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1228374 | 0.85 | GAA (0.41) | GAACCR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8513024 | 0.85 | CCR1 (0.42) | GAACCR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1229148 | 0.85 | GAA (0.48) | GAACCR1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557821-B2 | Microbiocidal heterocycles | SYNGENTA CROP PROTECTION, LLC (US) | 2013-10-15 | — | — | US | disclosed |
| EP-2464643-A1 | MICROBIOCIDAL HETEROCYCLES | Syngenta Participations AG (CH) | 2012-06-20 | — | — | EP | disclosed |
| US-20120142700-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-06-07 | — | — | US | disclosed |
| WO-2011018401-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142700-A1 | MICROBIOCIDAL HETEROCYCLES | MPO, CYP51A1, CYP1A1 | GAA 560/4885CCR1 487/4885CYP1A2 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.