Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033572 | 0.91 | MEN1 (0.66) | MEN1KMT2ATSHRALDH1A1HSD17B10 | |
| SCHEMBL29409695 | 0.91 | MEN1 (0.66) | MEN1KMT2ATSHRALDH1A1HSD17B10 | |
| SCHEMBL10261684 | 0.89 | HEXA (0.51) | MEN1KMT2ATSHRALDH1A1TP53 | |
| SCHEMBL29239556 | 0.87 | MEN1 (0.61) | MEN1KMT2ATSHRALDH1A1HSD17B10 | |
| Acrylic Acid SCHEMBL28997944 | 0.87 | MEN1 (0.65) | MEN1KMT2ATSHRALDH1A1HSD17B10 | |
| SCHEMBL9838180 | 0.86 | MEN1 (0.56) | MEN1KMT2ATSHRALDH1A1HSD17B10 | |
| SCHEMBL17158253 | 0.84 | ALDH1A1 (0.55) | MEN1KMT2ATSHRALDH1A1HSD17B10 | |
| SCHEMBL16865687 | 0.84 | ALDH1A1 (0.47) | MEN1KMT2ATSHRALDH1A1TP53 | |
| SCHEMBL10262183 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2ATSHRALDH1A1TP53 | |
| SCHEMBL10262179 | 0.83 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8025901-B2 | Bifunctional-modified hydrogels | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-09-27 | — | — | US | disclosed |
| US-20100209509-A1 | BIFUNCTIONAL-MODIFIED HYDROGELS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-08-19 | — | — | US | disclosed |
| US-7615593-B2 | Comprises interpenetrating polymer network/matrix (of collagen and/or gelatin) modified with endcapped polyalkylene glycol; drug delivery; for incorporation into bandages, surgical and dental wound packing material, diapers and catamenial devices | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100209509-A1 | BIFUNCTIONAL-MODIFIED HYDROGELS | PCNA, CDC25B, ALG1 | MEN1 3207/4885KMT2A 1670/4885TSHR 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.