SCHEMBL10262183

SCHEMBL10262183

C=CC(=O)OCCOCCN1C(=O)c2cccc3c(Cl)ccc(c23)C1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
LMNA P02545 4/20 0.50
KDM4E B2RXH2 3/20 0.50
MAPT P10636 4/20 0.47
POLB P06746 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
TSHR P16473 3/20 0.47
CYP1A2 P05177 1/20 0.47
ERCC1 P07992 1/20 0.47
ALOX12 P18054 1/20 0.47
FEN1 P39748 1/20 0.47
ERCC4 Q92889 1/20 0.47
HPGD P15428 1/20 0.47
KMT2A Q03164 9/20 0.44
MEN1 O00255 8/20 0.44
L3MBTL1 Q9Y468 5/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
USP2 O75604 1/20 0.44
MAPK1 P28482 3/20 0.42
HTT P42858 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10267905 0.93 LMNA (0.54) ALDH1A1LMNAKDM4EMAPTPOLB
SCHEMBL10262179 0.87 ALDH1A1 (0.56) ALDH1A1LMNAKDM4EMAPTPOLB
SCHEMBL10261684 0.84 HEXA (0.51) ALDH1A1KDM4EMAPTTSHRCYP1A2
SCHEMBL10261860 0.84 HDAC3 (0.53) ALDH1A1LMNAKDM4EMAPTPOLB
SCHEMBL10262440 0.84 HPGD (0.44) ALDH1A1LMNAKDM4EMAPTPOLB
SCHEMBL16865687 0.83 ALDH1A1 (0.47) ALDH1A1LMNAKDM4ETSHRHPGD
SCHEMBL12285609 0.83 MEN1 (0.56) ALDH1A1LMNAMAPTPOLBTDP1
SCHEMBL10262050 0.82 LMNA (0.59) ALDH1A1LMNAKDM4EMAPTPOLB
SCHEMBL21034453 0.81 PRMT1 (0.56) ALDH1A1LMNAKDM4EMAPTPOLB
SCHEMBL10267904 0.80 ALDH1A1 (0.60) ALDH1A1LMNAKDM4EMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211613-B2 prints, color filters, electronics, layer insulation films, wire covering films, optics, circuits, antireflection films, holograms and construction materials comprising a cured mixture of photosensitive resins and photoiniitiators having a naphthalimide structure DAI NIPPON PRINTING CO., LTD. (JP) 2012-07-03 US disclosed
US-8211613-B2 prints, color filters, electronics, layer insulation films, wire covering films, optics, circuits, antireflection films, holograms and construction materials comprising a cured mixture of photosensitive resins and photoiniitiators having a naphthalimide structure DAI NIPPON PRINTING CO., LTD. (JP) 2012-07-03 US disclosed
US-20080275154-A1 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition SAKAYORI KATSUYA 2008-11-06 US disclosed
US-20080275154-A1 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition SAKAYORI KATSUYA 2008-11-06 US disclosed
US-7410746-B2 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition DAI NIPPON PRINTING CO., LTD. (JP) 2008-08-12 US disclosed
US-7410746-B2 Photoradical polymerization initiator, radical generator, photosensitive compound and photosensitive resin composition containing these materials and product or its accessory portions using the composition DAI NIPPON PRINTING CO., LTD. (JP) 2008-08-12 US disclosed