Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12286264 | 0.90 | L3MBTL1 (0.61) | L3MBTL1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12285793 | 0.88 | L3MBTL1 (0.61) | L3MBTL1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL2563387 | 0.86 | L3MBTL1 (0.63) | L3MBTL1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12286181 | 0.85 | L3MBTL1 (0.61) | L3MBTL1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12285361 | 0.85 | L3MBTL1 (0.55) | L3MBTL1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL469216 | 0.84 | L3MBTL1 (0.66) | L3MBTL1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12285363 | 0.83 | L3MBTL1 (0.64) | L3MBTL1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12285358 | 0.82 | L3MBTL1 (0.57) | L3MBTL1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12285449 | 0.81 | L3MBTL1 (0.63) | L3MBTL1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12286146 | 0.81 | L3MBTL1 (0.56) | L3MBTL1NPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130035397-A1 | Anti-Viral Compounds | Kineta, Inc. (US) | 2013-02-07 | — | — | US | disclosed |
| US-20130035397-A1 | Anti-Viral Compounds | Kineta, Inc. (US) | 2013-02-07 | — | — | US | disclosed |
| WO-2011133712-A2 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2011-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035397-A1 | Anti-Viral Compounds | MAVS, EIF2AK2, IRF3 | L3MBTL1 1059/4885NPC1 1706/4885RAB9A 812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.