Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | OGG1 | O15527 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12285743 | 0.74 | HDAC6 (0.52) | HDAC6SMPD1 | |
| SCHEMBL23652719 | 0.74 | HDAC6 (0.41) | HDAC6 | |
| SCHEMBL12210531 | 0.74 | HDAC6 (0.60) | HDAC6HDAC8 | |
| SCHEMBL12283353 | 0.73 | MCHR1 (0.49) | — | |
| SCHEMBL12210478 | 0.72 | HDAC6 (0.57) | HDAC6HDAC2HDAC8 | |
| SCHEMBL31607767 | 0.71 | HDAC6 (0.36) | HDAC6 | |
| SCHEMBL27137687 | 0.71 | KMT2A (0.36) | HDAC6 | |
| SCHEMBL12210588 | 0.70 | HDAC6 (1.00) | HDAC6HDAC2HDAC8 | |
| SCHEMBL27138160 | 0.70 | HDAC6 (0.36) | HDAC6 | |
| SCHEMBL12210483 | 0.69 | HDAC6 (0.67) | HDAC6HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130163-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-10-20 | — | — | WO | disclosed |