Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930268 | 0.79 | KDM4E (0.35) | RXFP1MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL14913421 | 0.78 | CYP2D6 (0.36) | RXFP1MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL14912399 | 0.78 | MAP4K4 (0.36) | RXFP1MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL19965804 | 0.77 | BTK (0.38) | HDAC6RXFP1MAPTKDM4EALDH1A1 | |
| SCHEMBL23801513 | 0.73 | BTK (0.32) | RXFP1MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL31607767 | 0.71 | HDAC6 (0.36) | HDAC6ALDH1A1ALOX15POLB | |
| SCHEMBL14912888 | 0.71 | POLB (0.34) | KDM4EALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL27137687 | 0.71 | KMT2A (0.36) | HDAC6RXFP1MAPTKDM4EALDH1A1 | |
| SCHEMBL23652721 | 0.71 | — | — | |
| SCHEMBL27142451 | 0.71 | KCNJ1 (0.42) | MAPTGAARAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3851436-A1 | NOVEL HETEROAROMATIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2021-07-21 | — | — | EP | disclosed |