Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 16/20 | 0.47 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.47 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.47 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413826 | 1.00 | SLC9A3 (0.47) | SLC9A3TRPC6TRPC3TRPC7CYP2D6 | |
| SCHEMBL2408570 | 0.90 | TRPC6 (0.55) | SLC9A3TRPC6TRPC3TRPC7CYP2D6 | |
| SCHEMBL12290638 | 0.90 | TRPC6 (0.49) | SLC9A3TRPC6TRPC3TRPC7CYP2D6 | |
| SCHEMBL12291258 | 0.90 | TRPC6 (0.49) | SLC9A3TRPC6TRPC3TRPC7CYP2D6 | |
| SCHEMBL2369936 | 0.86 | TRPC6 (0.54) | SLC9A3TRPC6TRPC3TRPC7CYP2D6 | |
| SCHEMBL2413989 | 0.86 | TRPC6 (0.58) | SLC9A3TRPC6TRPC3TRPC7CYP2D6 | |
| SCHEMBL2409989 | 0.86 | TRPC6 (0.56) | SLC9A3TRPC6TRPC3TRPC7CYP2D6 | |
| SCHEMBL2409067 | 0.86 | TRPC6 (0.56) | SLC9A3TRPC6TRPC3TRPC7CYP2D6 | |
| SCHEMBL12291653 | 0.84 | TRPC6 (0.52) | SLC9A3TRPC6TRPC3TRPC7CYP2D6 | |
| SCHEMBL2409077 | 0.84 | TRPC6 (0.52) | SLC9A3TRPC6TRPC3TRPC7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011107474-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2011-09-09 | — | — | WO | disclosed |