Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.52 |
| ▸ | SLC9A3 | P48764 | 18/20 | 0.49 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.43 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12320495 | 1.00 | TRPC6 (0.52) | TRPC6SLC9A3TRPC3TRPC7CYP2D6 | |
| SCHEMBL2409863 | 1.00 | TRPC6 (0.52) | TRPC6SLC9A3TRPC3TRPC7CYP2D6 | |
| SCHEMBL2409077 | 1.00 | TRPC6 (0.52) | TRPC6SLC9A3TRPC3TRPC7CYP2D6 | |
| SCHEMBL14966618 | 0.89 | TRPC6 (0.52) | TRPC6SLC9A3CYP2D6 | |
| SCHEMBL14966575 | 0.89 | TRPC6 (0.52) | TRPC6SLC9A3CYP2D6 | |
| SCHEMBL2410171 | 0.89 | TRPC6 (0.52) | TRPC6SLC9A3CYP2D6 | |
| SCHEMBL12320194 | 0.87 | SLC9A3 (0.50) | TRPC6SLC9A3CYP2D6 | |
| SCHEMBL12363464 | 0.86 | TRPC6 (0.43) | TRPC6SLC9A3TRPC3TRPC7CYP2D6 | |
| SCHEMBL12290638 | 0.85 | TRPC6 (0.49) | TRPC6SLC9A3TRPC3TRPC7CYP2D6 | |
| SCHEMBL12291258 | 0.85 | TRPC6 (0.49) | TRPC6SLC9A3TRPC3TRPC7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011107474-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2011-09-09 | — | — | WO | disclosed |