Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 18/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20986111 | 0.80 | GRIN2B (0.50) | GRIN2BGRIN1 | |
| SCHEMBL22153089 | 0.79 | GRIN2B (0.42) | GRIN2BHSD17B10GRIN1 | |
| SCHEMBL16913922 | 0.78 | GRIN2B (0.55) | GRIN2BGRIN1 | |
| SCHEMBL16302844 | 0.78 | CYP11B1 (0.47) | GRIN2B | |
| SCHEMBL3781277 | 0.77 | GRIN2B (0.49) | GRIN2BHSD17B10GRIN1 | |
| SCHEMBL28518318 | 0.77 | KDM4E (0.49) | GRIN2BGRIN1 | |
| SCHEMBL2371256 | 0.77 | HSD17B10 (0.44) | GRIN2BHSD17B10GRIN1 | |
| SCHEMBL16302840 | 0.76 | HSD17B10 (0.35) | GRIN2BHSD17B10 | |
| SCHEMBL16302851 | 0.76 | HSD17B10 (0.35) | GRIN2BHSD17B10 | |
| SCHEMBL797478 | 0.75 | DGAT1 (0.41) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011110575-A1 | DERIVATIVES OF 2-[2-(BENZO- OR PYRIDO-) THIAZOLYLAMINO]-6-AMINOPYRIDINE, USEFUL IN THE TREATMENT OF RESPIRATORIC, ALLERGIC OR INFLAMMATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2011-09-15 | — | — | WO | disclosed |