Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 19/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22775410 | 0.78 | ALDH1A1 (0.44) | KDM4EALDH1A1 | |
| SCHEMBL3589940 | 0.78 | GRIN2B (0.51) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL12291376 | 0.77 | GRIN2B (0.40) | GRIN2BGRIN1 | |
| SCHEMBL28523558 | 0.77 | GRIN2B (0.77) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL4485443 | 0.75 | NTSR1 (0.52) | ALDH1A1 | |
| SCHEMBL18363131 | 0.74 | GRIN2B (0.69) | GRIN2B | |
| SCHEMBL18363127 | 0.74 | GRIN2B (0.69) | GRIN2B | |
| SCHEMBL20596219 | 0.74 | RAB9A (0.47) | KDM4EALDH1A1CYP2C9 | |
| SCHEMBL31528647 | 0.74 | FPR2 (0.45) | KDM4EALDH1A1CYP2C9 | |
| SCHEMBL3046102 | 0.73 | PPARD (0.41) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026094-B | Substituted 4-azaindoles and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2021-02-09 | — | — | CN | disclosed |