Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 6/20 | 0.38 |
| ▸ | TGM2 | P21980 | 5/20 | 0.38 |
| ▸ | NPY1R | P25929 | 3/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367531 | 0.86 | MEN1 (0.55) | MEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL27911007 | 0.86 | TGM2 (0.42) | C3AR1FOLH1MEN1GAAKMT2A | |
| SCHEMBL7364210 | 0.86 | MEN1 (0.55) | MEN1GAAKMT2A | |
| SCHEMBL1486276 | 0.86 | MEN1 (0.55) | MEN1GAAKMT2A | |
| SCHEMBL29005731 | 0.85 | C3AR1 (0.43) | C3AR1FOLH1MEN1KMT2ANPY4R | |
| SCHEMBL12971304 | 0.85 | C3AR1 (0.43) | C3AR1FOLH1MEN1KMT2ANPY4R | |
| Hydrochloric Acid SCHEMBL8630295 | 0.85 | MEN1 (0.54) | MEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL10444447 | 0.85 | MEN1 (0.54) | MEN1GAAKMT2A | |
| Water SCHEMBL10332189 | 0.85 | MEN1 (0.54) | MEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL7264801 | 0.85 | MEN1 (0.54) | MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160314241-A1 | DRUG DISCOVERY METHOD | Keddem Bioscience Ltd. (IL) | 2016-10-27 | — | — | US | disclosed |
| US-9405885-B2 | Drug discovery method | Keddem Bioscience Ltd. (IL) | 2016-08-02 | — | — | US | disclosed |
| US-8019550-B2 | Drug discovery method | Keddem Bioscience Ltd. (IL) | 2011-09-13 | — | — | US | disclosed |