Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.54 |
| ▸ | PPARG known ✓ | P37231 | 3/20 | 0.41 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.41 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.41 |
| ▸ | ITGB3 known ✓ | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B known ✓ | P08514 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 8/20 | 0.47 |
| ▸ | CTSS | P25774 | 5/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10444447 | 1.00 | MEN1 (0.54) | MEN1GAAKMT2ACTSKCTSS | |
| Hydrochloric Acid SCHEMBL7264801 | 1.00 | MEN1 (0.54) | MEN1GAAKMT2ACTSKCTSS | |
| Hydrochloric Acid SCHEMBL7304854 | 0.99 | MEN1 (0.52) | MEN1GAAKMT2ACTSKCTSS | |
| Hydrochloric Acid SCHEMBL10723070 | 0.99 | MEN1 (0.52) | MEN1GAAKMT2ACTSKCTSS | |
| Hydrochloric Acid SCHEMBL10932432 | 0.99 | MEN1 (0.52) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL2367531 | 0.99 | MEN1 (0.55) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL7364210 | 0.99 | MEN1 (0.55) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL1486276 | 0.99 | MEN1 (0.55) | MEN1GAAKMT2ACTSKCTSS | |
| Water SCHEMBL10332189 | 0.97 | MEN1 (0.54) | MEN1GAAKMT2ACTSKCTSS | |
| Water SCHEMBL10332190 | 0.97 | MEN1 (0.54) | MEN1GAAKMT2ACTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304254-A | Synthesis method of endotoxin detection reagent fluorogenic substrate | 上海瀚诺威生物科技有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-108864006-A | N- tertbutyloxycarbonyl-N '-（Pentamethyl Dihydrobenzofuranes -5- sulfonyl)-L-arginine synthetic method | 上海吉奉生物科技有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-113698457-B | Preparation method of gonadorelin acetate | 上海丽珠制药有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-117304254-A | Synthesis method of endotoxin detection reagent fluorogenic substrate | 上海瀚诺威生物科技有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117304254-A | Synthesis method of endotoxin detection reagent fluorogenic substrate | 上海瀚诺威生物科技有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-108864006-A | N- tertbutyloxycarbonyl-N '-（Pentamethyl Dihydrobenzofuranes -5- sulfonyl)-L-arginine synthetic method | 上海吉奉生物科技有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-106478759-A | Shellfish chlolic acid derivatives difficult to understand and its production and use | 陕西合成药业股份有限公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-106467494-A | Amino-acid ester soluble derivative of laevo-ornidazole and application thereof | 陕西合成药业股份有限公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-102617380-B | Carbonic acid diester water-soluble derivant of amino acid and propofol, and application of carbonic acid diester water-soluble derivant of amino acid and propofol | CHENGDU YIPING PHARMACEUTICAL SCIENCE & DEV CO LTD | 2014-04-02 | — | — | CN | disclosed |
| CN-102617380-A | Carbonic acid diester water-soluble derivant of amino acid and propofol, and application of carbonic acid diester water-soluble derivant of amino acid and propofol | CHENGDU YIPING MEDICAL TECHNOLOGY DEV CO LTD | 2012-08-01 | — | — | CN | disclosed |
| CN-102391137-A | Water-soluble amino acid ester derivative of propofol and application thereof | CHENGDU YIPING MEDICAL TECHNOLOGY DEV CO LTD | 2012-03-28 | — | — | CN | disclosed |
| EP-0542525-B1 | Antithrombotic agents | LILLY CO ELI (US) | 1998-07-08 | — | — | EP | disclosed |
| US-5416093-A | DIPEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| US-5252566-A | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0542525-A2 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| EP-0446699-A1 | Inhibitors of nitric oxide biosynthesis | MERRELL PHARMACEUTICALS INC. (US) | 1991-09-18 | — | — | EP | disclosed |
| EP-0360390-A1 | Spirolactam derivatives | GLAXO GROUP LIMITED (GB) | 1990-03-28 | — | — | EP | disclosed |
| EP-0137742-B1 | PROCESS FOR PRODUCING ARGINYL-P-NITROANILIDE | NITTO BOSEKI CO., LTD. (JP) | 1986-09-17 | — | — | EP | disclosed |
| EP-0137742-A1 | Process for producing arginyl-p-nitroanilide | NITTO BOSEKI CO., LTD. (JP) | 1985-04-17 | — | — | EP | disclosed |