Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 2/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19661469 | 1.00 | LGALS8 (0.33) | LGALS8LGALS3 | |
| SCHEMBL20334521 | 1.00 | LGALS8 (0.33) | LGALS8LGALS3 | |
| SCHEMBL23660466 | 0.87 | CA1 (0.33) | — | |
| SCHEMBL21481959 | 0.87 | — | — | |
| SCHEMBL21123603 | 0.85 | — | — | |
| SCHEMBL14624334 | 0.85 | — | — | |
| SCHEMBL14537230 | 0.85 | — | — | |
| SCHEMBL22317546 | 0.85 | — | — | |
| SCHEMBL26253255 | 0.85 | — | — | |
| SCHEMBL14295972 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109427-A2 | IMPROVING THE BIOLOGICAL ACTIVITY OF SIRNA THROUGH MODULATION OF ITS THERMODYNAMIC PROFILE | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |