Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 2/20 | 0.33 |
| ▸ | AMY2A | P04746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14295971 | 0.81 | — | — | |
| SCHEMBL14537229 | 0.81 | — | — | |
| SCHEMBL22317545 | 0.81 | — | — | |
| SCHEMBL6241156 | 0.78 | LGALS8 (0.34) | LGALS8AMY2A | |
| SCHEMBL6545037 | 0.78 | LGALS8 (0.34) | LGALS8AMY2A | |
| SCHEMBL12149515 | 0.78 | LGALS8 (0.31) | LGALS8AMY2A | |
| SCHEMBL6544623 | 0.78 | LGALS8 (0.34) | LGALS8AMY2A | |
| SCHEMBL6544477 | 0.78 | LGALS8 (0.34) | LGALS8AMY2A | |
| SCHEMBL20900473 | 0.78 | — | — | |
| SCHEMBL12154024 | 0.77 | LGALS8 (0.30) | LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109427-A2 | IMPROVING THE BIOLOGICAL ACTIVITY OF SIRNA THROUGH MODULATION OF ITS THERMODYNAMIC PROFILE | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |