⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14537229 | 1.00 | — | — | |
| SCHEMBL14295971 | 1.00 | — | — | |
| SCHEMBL16943046 | 0.85 | — | — | |
| SCHEMBL26652153 | 0.82 | FGF1 (0.33) | — | |
| SCHEMBL10310995 | 0.82 | FGF1 (0.33) | — | |
| SCHEMBL13222901 | 0.82 | FGF1 (0.33) | — | |
| SCHEMBL12253802 | 0.82 | FGF1 (0.33) | — | |
| SCHEMBL10001262 | 0.82 | FGF1 (0.33) | — | |
| SCHEMBL20329200 | 0.82 | — | — | |
| SCHEMBL26474211 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11566070-B2 | Agents that modulate TMEM230 as angiogenesis regulators and that detect TMEM230 as markers of metastasis | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2023-01-31 | — | — | US | disclosed |
| US-20200247882-A1 | AGENTS THAT MODULATE TMEM230 AS ANGIOGENESIS REGULATORS AND THAT DETECT TMEM230 AS MARKERS OF METASTASIS | REINBOLD, Rolland Alvons (IT) | 2020-08-06 | — | — | US | disclosed |