Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.46 |
| ▸ | ITGAM | P11215 | 3/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12292499 | 0.90 | MEN1 (0.49) | MEN1KMT2ARECQLBLMTDP1 | |
| SCHEMBL683937 | 0.85 | ITGB2 (0.58) | MEN1KMT2ARECQLBLMTDP1 | |
| SCHEMBL12292503 | 0.84 | ENPP2 (0.48) | MEN1KMT2ARECQLBLMTDP1 | |
| SCHEMBL12291206 | 0.84 | ENPP2 (0.54) | MEN1KMT2ARECQLBLMTDP1 | |
| SCHEMBL12292506 | 0.84 | ENPP2 (0.54) | MEN1KMT2ARECQLBLMTDP1 | |
| SCHEMBL12291214 | 0.84 | ITGB2 (0.59) | MEN1KMT2ARECQLBLMTDP1 | |
| SCHEMBL12291201 | 0.84 | MEN1 (0.65) | MEN1KMT2ARECQLBLMTDP1 | |
| SCHEMBL12292504 | 0.84 | MEN1 (0.52) | MEN1KMT2ARECQLBLMTDP1 | |
| SCHEMBL12292508 | 0.82 | ENPP2 (0.57) | MEN1KMT2ARECQLBLMTDP1 | |
| SCHEMBL12292498 | 0.82 | MEN1 (0.47) | MEN1KMT2ARECQLBLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011133719-A2 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2011-10-27 | — | — | WO | disclosed |