Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.58 |
| ▸ | ITGAM | P11215 | 3/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12291206 | 0.91 | ENPP2 (0.54) | ITGB2ITGAMENPP2MEN1KMT2A | |
| SCHEMBL12291214 | 0.91 | ITGB2 (0.59) | ITGB2ITGAMENPP2MEN1KMT2A | |
| SCHEMBL12292506 | 0.91 | ENPP2 (0.54) | ITGB2ITGAMENPP2MEN1KMT2A | |
| SCHEMBL12291201 | 0.91 | MEN1 (0.65) | ITGB2ITGAMENPP2MEN1KMT2A | |
| SCHEMBL12292497 | 0.90 | ENPP2 (0.69) | ITGB2ITGAMENPP2MEN1KMT2A | |
| SCHEMBL46219 | 0.89 | ALDH1A1 (0.61) | ENPP2MEN1KMT2ARECQLTDP1 | |
| SCHEMBL12292508 | 0.89 | ENPP2 (0.57) | ITGB2ITGAMENPP2MEN1KMT2A | |
| SCHEMBL12291195 | 0.88 | MEN1 (0.52) | ITGB2ITGAMENPP2MEN1KMT2A | |
| SCHEMBL12292502 | 0.88 | EP300 (0.57) | ITGB2ITGAMENPP2MEN1KMT2A | |
| SCHEMBL12292505 | 0.87 | ENPP2 (0.58) | ITGB2ITGAMENPP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010255-A1 | Compounds and Methods for Regulating Integrins | ATEGRIN, INC. | 2012-01-12 | — | — | US | disclosed |
| US-20120010255-A1 | Compounds and Methods for Regulating Integrins | ATEGRIN, INC. | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010255-A1 | Compounds and Methods for Regulating Integrins | ITGB8, ITGB3, ITGAM | ITGB2 5/4885ITGAM 3/4885ENPP2 1581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.