Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13521671 | 1.00 | BACE1 (0.51) | BACE1CA12CA1CA2CA9 | |
| SCHEMBL3144940 | 1.00 | BACE1 (0.51) | BACE1CA12CA1CA2CA9 | |
| SCHEMBL5097623 | 0.84 | LMNA (0.50) | CA12CA1CA2CA9LMNA | |
| SCHEMBL6376097 | 0.84 | PLAU (0.45) | CA12CA1CA2CA9PLAU | |
| SCHEMBL6375277 | 0.83 | ALDH1A1 (0.50) | CA12CA1CA2CA9PLAU | |
| SCHEMBL8444209 | 0.82 | LMNA (0.46) | CA12CA1CA2CA9PLAU | |
| SCHEMBL12295603 | 0.82 | PLAU (0.47) | BACE1CA12CA1CA2CA9 | |
| SCHEMBL8811364 | 0.82 | LMNA (0.48) | CA12CA1CA2CA9PLAU | |
| SCHEMBL15184648 | 0.82 | ALDH1A1 (0.53) | BACE1CA12CA1CA2CA9 | |
| SCHEMBL8363864 | 0.82 | ALDH1A1 (0.53) | BACE1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011104649-A1 | PEPTIDE ANALOGUES | PFIZER LIMITED (GB) | 2011-09-01 | — | — | WO | disclosed |
| US-7368605-B2 | Variously substituted derivatives of guanidine, and their use as medicines with anti-diabetes and/or anti-obesity activity | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2008-05-06 | — | — | US | disclosed |
| US-7368605-B2 | Variously substituted derivatives of guanidine, and their use as medicines with anti-diabetes and/or anti-obesity activity | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2008-05-06 | — | — | US | disclosed |