Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.33 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.33 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.33 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.33 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.33 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.33 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.33 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.33 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.33 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.33 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.33 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.33 |
| ▸ | PSMA6 | P60900 | 2/20 | 0.33 |
| ▸ | PSMA8 | Q8TAA3 | 2/20 | 0.33 |
| ▸ | PSMB7 | Q99436 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229512 | 1.00 | PSMB11 (0.33) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL8227700 | 0.91 | — | — | |
| SCHEMBL8134568 | 0.91 | — | — | |
| SCHEMBL8135209 | 0.91 | — | — | |
| SCHEMBL25963670 | 0.83 | — | — | |
| SCHEMBL28918840 | 0.83 | — | — | |
| SCHEMBL3852666 | 0.82 | PSMB11 (0.33) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL7991204 | 0.79 | — | — | |
| SCHEMBL7991200 | 0.79 | — | — | |
| SCHEMBL10338317 | 0.79 | PSMB1 (0.36) | PSMB11PSMA7PSMB1PSMA1PSMA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4676880-B2 | — | — | 2011-04-27 | — | — | JP | claimed |
| US-20090325836-A1 | Cyclooct-(EN-)YL Derivatives for Use as Fragrances | GIVAUDAN SA (CH) | 2009-12-31 | — | — | US | claimed |
| EP-1555998-B1 | CYCLOOCT-(EN-)YL DERIVATIVES FOR USE AS FRAGRANCES | GIVAUDAN SA (CH) | 2009-07-29 | — | — | EP | claimed |
| JP-2006512470-A | — | — | 2006-04-13 | — | — | JP | claimed |
| US-20060014663-A1 | Cyclooct-(en-)yl derivatives for use as fragrances | GIVAUDAN SA (CH) | 2006-01-19 | — | — | US | claimed |
| EP-1555998-A1 | CYCLOOCT-(EN-)YL DERIVATIVES FOR USE AS FRAGRANCES | Givaudan SA (CH) | 2005-07-27 | — | — | EP | claimed |
| WO-2004035017-A1 | CYCLOOCT-(EN-)YL DERIVATIVES FOR USE AS FRAGRANCES | GIVAUDAN SA (CH) | 2004-04-29 | — | — | WO | claimed |
| US-7888309-B2 | 1-Alkanoyl-substituted cyclooctenes having agrestic, natural, and floral, green, woody odor notes; preferably, 1-cyclooct-3-enylethanone, 1-cyclooct-3-enylpropan-1-one, 1-cyclooct-3-enyl-2-methylpropan-1-one; cleaning compounds; personal care; cosmetics; detergents; fabric softeners; shampoos; gels etc. | GIVAUDAN SA (CH) | 2011-02-15 | — | — | US | disclosed |
| US-20090325836-A1 | Cyclooct-(EN-)YL Derivatives for Use as Fragrances | GIVAUDAN SA (CH) | 2009-12-31 | — | — | US | disclosed |
| US-7605118-B2 | 1-cyclooct-3-enylpropan-1-one; -cyclooct-3-enylpropan-1-ol; perfume, household product, laundry product, body care product or cosmetic | GIVAUDAN SA (CH) | 2009-10-20 | — | — | US | disclosed |
| EP-1555998-B1 | CYCLOOCT-(EN-)YL DERIVATIVES FOR USE AS FRAGRANCES | GIVAUDAN SA (CH) | 2009-07-29 | — | — | EP | disclosed |
| US-20060014663-A1 | Cyclooct-(en-)yl derivatives for use as fragrances | GIVAUDAN SA (CH) | 2006-01-19 | — | — | US | disclosed |
| EP-1555998-A1 | CYCLOOCT-(EN-)YL DERIVATIVES FOR USE AS FRAGRANCES | Givaudan SA (CH) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004035017-A1 | CYCLOOCT-(EN-)YL DERIVATIVES FOR USE AS FRAGRANCES | GIVAUDAN SA (CH) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014663-A1 | Cyclooct-(en-)yl derivatives for use as fragrances | ENY2, FPR1, CNR1 | PSMB11 2968/4885PSMA7 3416/4885PSMB1 2984/4885 |
| US-20090325836-A1 | Cyclooct-(EN-)YL Derivatives for Use as Fragrances | ENY2, FPR1, CNR1 | PSMB11 2968/4885PSMA7 3416/4885PSMB1 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.