Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.84 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.83 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.83 |
| ▸ | KCND2 | Q9NZV8 | 5/20 | 0.83 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410599 | 1.00 | SLC6A4 (0.84) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12327948 | 1.00 | SLC6A4 (0.84) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| Hydrochloric Acid SCHEMBL439835 | 0.99 | KCNA5 (0.85) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL410072 | 0.92 | SLC6A4 (0.84) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL13097960 | 0.92 | SLC6A4 (0.84) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12327983 | 0.92 | SLC6A4 (0.84) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12122779 | 0.92 | SLC6A4 (0.84) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL14390503 | 0.92 | SLC6A4 (0.84) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL14851637 | 0.92 | SLC6A4 (0.84) | SLC6A4KCNA5SCN5AKCND2KCNH2 | |
| SCHEMBL12296102 | 0.92 | SLC6A4 (0.84) | SLC6A4KCNA5SCN5AKCND2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022098-B2 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | CARDIOME PHARMA CORP. (CA) | 2011-09-20 | — | — | US | disclosed |
| US-20100152276-A1 | DEUTERATED AMINOCYCLOHEXYL ETHER COMPOUNDS AND PROCESSES FOR PREPARING SAME | CARDIOME PHARMA CORP. (CA) | 2010-06-17 | — | — | US | disclosed |
| US-7705036-B2 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | CARDIOME PHARMA CORP. (CA) | 2010-04-27 | — | — | US | disclosed |
| US-20070088075-A1 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | CARDIOME PHARMA CORP. (CA) | 2007-04-19 | — | — | US | disclosed |
| US-20070088075-A1 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | CARDIOME PHARMA CORP. (CA) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088075-A1 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | DDC, HDHD5, DDT | SLC6A4 2668/4885KCNA5 2363/4885SCN5A 4208/4885 |
| US-20100152276-A1 | DEUTERATED AMINOCYCLOHEXYL ETHER COMPOUNDS AND PROCESSES FOR PREPARING SAME | DDC, HDHD5, DDT | SLC6A4 2668/4885KCNA5 2363/4885SCN5A 4208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.