Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1230554 | 0.98 | ALDH1A1 (0.39) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL2521791 | 0.79 | TSHR (0.48) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL2521792 | 0.76 | TSHR (0.48) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL4904636 | 0.72 | ALDH1A1 (0.38) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL17520209 | 0.72 | TSHR (0.44) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL17520242 | 0.72 | TSHR (0.44) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL9211254 | 0.71 | TSHR (0.48) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL9211215 | 0.71 | TSHR (0.48) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL23539727 | 0.71 | TSHR (0.52) | ALDH1A1LMNATSHRMAPTABCC4 | |
| SCHEMBL26513499 | 0.71 | TSHR (0.52) | ALDH1A1LMNATSHRMAPTABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462174-A1 | BINDING AGENTS BASED ON HIGHLY BRANCHED POLYOLEFINS COMPRISING SILANE GROUPS | Wacker Chemie AG (DE) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011015547-A1 | BINDING AGENTS BASED ON HIGHLY BRANCHED POLYOLEFINS COMPRISING SILANE GROUPS | WACKER CHEMIE AG (DE) | 2011-02-10 | — | — | WO | disclosed |