Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12294725 | 0.83 | HRH3 (0.48) | HRH3ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL112580 | 0.79 | ALDH1A1 (0.54) | KMT2ARAD52RXFP1MAPTKDM4E | |
| SCHEMBL7365166 | 0.79 | CHKA (0.50) | HRH3F2PRSS1PRSS2PRSS3 | |
| SCHEMBL27483821 | 0.78 | POLB (0.40) | HRH3ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL1645442 | 0.78 | MAPT (0.57) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL111728 | 0.78 | ALDH1A1 (0.57) | KMT2AMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL4029277 | 0.78 | ALDH1A1 (0.57) | KMT2AMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL4029118 | 0.78 | ALDH1A1 (0.57) | KMT2AMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL39888 | 0.76 | LMNA (0.52) | KMT2AMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL27603139 | 0.76 | HRH3 (0.41) | HRH3ITGB3ITGA2BF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113606-A1 | ANTI-INFECTIVE COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2011-09-22 | — | — | WO | disclosed |