Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12296684 | 0.91 | HTR1A (0.34) | ALDH1A1TSHRPIK3CDHTR1ADRD2 | |
| SCHEMBL10760994 | 0.83 | ALDH1A1 (0.35) | ALDH1A1TSHRKDM4E | |
| SCHEMBL11348671 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HRH4TSHRCYP1A2HRH2 | |
| SCHEMBL11938145 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HRH4TSHRCYP1A2HRH2 | |
| SCHEMBL419073 | 0.80 | — | — | |
| SCHEMBL2510802 | 0.78 | — | — | |
| SCHEMBL12245087 | 0.77 | ALDH1A1 (0.34) | ALDH1A1HRH4TSHRCYP1A2HRH2 | |
| SCHEMBL5444539 | 0.75 | ALDH1A1 (0.61) | ALDH1A1TSHRDNM1KDM4ESMN1; SMN2 | |
| SCHEMBL5452780 | 0.75 | ALDH1A1 (0.61) | ALDH1A1TSHRDNM1KDM4ESMN1; SMN2 | |
| SCHEMBL4543525 | 0.75 | ALDH1A1 (0.61) | ALDH1A1TSHRDNM1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110313147-A1 | CHROMATOGRAPHIC MATERIAL FOR THE ABSORPTION OF PROTEINS AT PHYSIOLOGICAL IONIC STRENGTH | PALL CORPORATION (US) | 2011-12-22 | — | — | US | disclosed |
| US-8021889-B2 | Chromatographic material for the absorption of proteins at physiological ionic strength | PALL CORPORATION (US) | 2011-09-20 | — | — | US | disclosed |
| US-20070151910-A1 | Chromatographic material for the absorption of proteins at physiological ionic strength | PALL CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313147-A1 | CHROMATOGRAPHIC MATERIAL FOR THE ABSORPTION OF PROTEINS AT PHYSIOLOGICAL IONIC STRENGTH | SLC7A1, MAX, STAMBP | ALDH1A1 4708/4885HRH4 950/4885TSHR 1992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.