Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132633 | 0.94 | ALDH1A1 (0.33) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL6478540 | 0.88 | ALDH1A1 (0.30) | ALDH1A1TSHRHSD17B10 | |
| Bromide SCHEMBL7018789 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL1228610 | 0.88 | — | — | |
| SCHEMBL8013160 | 0.88 | ALDH1A1 (0.30) | ALDH1A1TSHRHSD17B10 | |
| Bromide SCHEMBL7024463 | 0.88 | ALDH1A1 (0.30) | ALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL1230150 | 0.88 | ALDH1A1 (0.30) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7033411 | 0.88 | ALDH1A1 (0.30) | ALDH1A1TSHRHSD17B10 | |
| Fluoride Ion SCHEMBL1229303 | 0.88 | ALDH1A1 (0.30) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL1601978 | 0.88 | ALDH1A1 (0.30) | ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746134-B1 | CURABLE COMPOSITION WITH IMPROVED CURABILITY AND ADHESIVENESS | KANEKA CORP (JP) | 2019-09-04 | — | — | EP | disclosed |
| EP-1746135-B1 | CURABLE COMPOSITION | KANEKA CORP (JP) | 2019-05-29 | — | — | EP | disclosed |
| US-7973108-B2 | Curable composition | KANEKA CORPORATION (JP) | 2011-07-05 | — | — | US | disclosed |
| US-7910681-B2 | Curable composition having improved adhesion | KANEKA CORPORATION (JP) | 2011-03-22 | — | — | US | disclosed |
| US-7893170-B2 | Curable composition having improved curability and adhesion | KANEKA CORPORATION (JP) | 2011-02-22 | — | — | US | disclosed |
| US-20080319152-A1 | Curable Composition | KANEKA CORPORATION (JP) | 2008-12-25 | — | — | US | disclosed |
| US-20080194773-A1 | Polysiloxane from silanetriol group, a titanium, aluminum or a zirconium catalyst, and a low molecular weight compound containing a hydrolyzable silicon group; sealants, adhesives | KANEKA CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
| US-20080076878-A1 | Organic polymer having a silane tiol group, a titanium, aluminum or a zirconium catalyst, and a low molecular weight compound containing a hydrolyzable silicon group; sealants, adhesives | KANEKA CORPORATION (JP) | 2008-03-27 | — | — | US | disclosed |
| EP-1746135-A1 | CURABLE COMPOSITION | Kaneka Corporation (JP) | 2007-01-24 | — | — | EP | disclosed |
| EP-1746133-A1 | CURABLE COMPOSITION IMPROVED IN ADHESIVENESS | Kaneka Corporation (JP) | 2007-01-24 | — | — | EP | disclosed |
| EP-1746134-A1 | CURABLE COMPOSITION WITH IMPROVED CURABILITY AND ADHESIVENESS | Kaneka Corporation (JP) | 2007-01-24 | — | — | EP | disclosed |