Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14078885 | 0.89 | ACP1 (0.43) | ACP1TLR7KMT2APOLBRAD52 | |
| SCHEMBL12245207 | 0.86 | ACP1 (0.43) | ACP1TLR7KMT2APOLBRAD52 | |
| SCHEMBL7831685 | 0.85 | KDM4E (0.43) | ACP1TLR7KMT2APOLBRAD52 | |
| SCHEMBL12296506 | 0.82 | ACP1 (0.38) | ACP1TLR7KMT2APOLBRAD52 | |
| SCHEMBL12245264 | 0.80 | KDM4E (0.59) | KMT2APOLBMEN1KDM4EMAPT | |
| SCHEMBL843109 | 0.69 | KDM4E (0.49) | ACP1TLR7KMT2APOLBRAD52 | |
| SCHEMBL31197385 | 0.69 | KDM4E (0.49) | ACP1TLR7KMT2APOLBRAD52 | |
| SCHEMBL8123589 | 0.68 | ESR1 (0.35) | TLR7KMT2AMEN1KDM4EMAPT | |
| SCHEMBL12245273 | 0.67 | POLB (0.39) | TLR7KMT2APOLBRAD52APP | |
| SCHEMBL8124811 | 0.66 | ESR1 (0.40) | TLR7KMT2APOLBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130096103-A1 | IMIDAZOQUINOLINE COMPOUNDS | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2013-04-18 | — | — | US | disclosed |
| US-20110217323-A1 | IMIDAZOQUINOLINE COMPOUNDS | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2011-09-08 | — | — | US | disclosed |
| US-20080213308-A1 | Imidazoquinoline Compounds | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096103-A1 | IMIDAZOQUINOLINE COMPOUNDS | IFNG, IRF3, MYD88 | ACP1 3545/4885TLR7 13/4885KMT2A 732/4885 |
| US-20110217323-A1 | IMIDAZOQUINOLINE COMPOUNDS | IFNG, IRF3, MYD88 | ACP1 3545/4885TLR7 13/4885KMT2A 732/4885 |
| US-20080213308-A1 | Imidazoquinoline Compounds | IFNG, IRF3, MYD88 | ACP1 3545/4885TLR7 13/4885KMT2A 732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.