Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127865 | 0.82 | LMNA (0.39) | SMN1; SMN2CRHR1TSHRMAPTNR3C1 | |
| SCHEMBL7831685 | 0.80 | KDM4E (0.43) | ESR1SMN1; SMN2TLR7KDM4EGAA | |
| SCHEMBL8124811 | 0.75 | ESR1 (0.40) | ESR1SMN1; SMN2TSHRTLR7MAPT | |
| SCHEMBL14340740 | 0.74 | TLR8 (0.37) | CRHR1TSHRTLR8TLR7KDM4E | |
| SCHEMBL12245207 | 0.71 | ACP1 (0.43) | ESR1SMN1; SMN2TLR7KDM4EMAPT | |
| SCHEMBL14078885 | 0.69 | ACP1 (0.43) | ESR1TLR7KDM4EMAPTMEN1 | |
| SCHEMBL12296904 | 0.68 | ACP1 (0.42) | ESR1SMN1; SMN2TLR7KDM4EMAPT | |
| SCHEMBL12245264 | 0.67 | KDM4E (0.59) | SMN1; SMN2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1140629 | 0.66 | PIK3CA (0.31) | — | |
| SCHEMBL8121147 | 0.64 | TLR7 (0.41) | SMN1; SMN2TSHRTLR7HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708772-B1 | IMIDAZO [4,5-c]PYRIDIN-4-AMINES | MINNESOTA MINING & MFG (US) | 2000-08-23 | — | — | EP | disclosed |