Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 11/20 | 0.55 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12298084 | 0.83 | PGR (0.58) | PGRARMAPTCA12CA9 | |
| SCHEMBL5032299 | 0.80 | PGR (0.50) | PGRARNR3C1NR3C2MEN1 | |
| SCHEMBL12886106 | 0.70 | PGR (0.74) | PGRARNR3C1NR3C2MEN1 | |
| SCHEMBL16309154 | 0.69 | PGR (0.54) | PGRARNR3C1NR3C2MEN1 | |
| SCHEMBL17821013 | 0.68 | MEN1 (0.55) | MEN1MAPTKMT2ACYP11B1CYP11B2 | |
| SCHEMBL5034452 | 0.68 | PGR (0.52) | PGRARNR3C1NR3C2 | |
| SCHEMBL5038438 | 0.68 | PGR (0.49) | PGRARNR3C1NR3C2 | |
| SCHEMBL5034792 | 0.68 | PGR (0.52) | PGRARNR3C1NR3C2CA12 | |
| SCHEMBL1315813 | 0.68 | ESR1 (0.53) | PGRMEN1MAPTKMT2AMAOA | |
| SCHEMBL12298172 | 0.67 | MAPT (0.54) | MEN1MAPTKMT2ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951938-B2 | Combinatorial rosamine library to detect cell-state switching | NEW YORK UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-8951938-B2 | Combinatorial rosamine library to detect cell-state switching | NEW YORK UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-8026110-B2 | For detecting and imaging cells; solid phase synthesis | NEW YORK UNIVERSITY (US) | 2011-09-27 | — | — | US | disclosed |
| US-20090227467-A1 | COMBINATORIAL ROSAMINE LIBRARY TO DETECT CELL-STATE SWITCHING | NEW YORK UNIVERSITY (US) | 2009-09-10 | — | — | US | disclosed |
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124751-A1 | COMBINATORIAL ROSAMINE LIBRARY AND USES THEREOF | RXFP1, RXFP2, CX3CR1 | PGR 226/4885AR 1801/4885NR3C1 4660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.