SCHEMBL12299489

SCHEMBL12299489

COc1ccccc1NC(=O)/C(=N\Nc1ccccc1C(=O)O)C(C)=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
MAPT P10636 3/20 0.58
MAPK1 P28482 2/20 0.58
KMT2A Q03164 6/20 0.58
POLB P06746 2/20 0.55
CASP6 P55212 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
MEN1 O00255 5/20 0.52
RECQL P46063 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
GAA P10253 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
RAB9A P51151 5/20 0.50
NPC1 O15118 3/20 0.50
GRIK1 P39086 1/20 0.50
LMNA P02545 1/20 0.48
TRPA1 O75762 1/20 0.47
TRPM8 Q7Z2W7 1/20 0.47
FABP3 P05413 1/20 0.47
FABP4 P15090 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12299510 0.90 DHODH (0.54) ALDH1A1MAPTMAPK1KMT2APOLB
SCHEMBL764924 0.86 ALDH1A1 (0.44) ALDH1A1MAPTMAPK1KMT2APOLB
SCHEMBL12998571 0.86 ALDH1A1 (0.65) ALDH1A1MAPTMAPK1KMT2APOLB
SCHEMBL12299491 0.84 ALDH1A1 (0.58) ALDH1A1MAPTMAPK1KMT2APOLB
SCHEMBL24384619 0.84 MAPT (0.53) ALDH1A1MAPTMAPK1KMT2APOLB
SCHEMBL12299580 0.84 NPC1 (0.51) ALDH1A1MAPTMAPK1KMT2APOLB
SCHEMBL13707250 0.84 MAPT (0.53) ALDH1A1MAPTMAPK1KMT2APOLB
SCHEMBL12299493 0.83 ALDH1A1 (0.63) ALDH1A1MAPTMAPK1KMT2APOLB
SCHEMBL13115109 0.83 ALDH1A1 (0.63) ALDH1A1MAPTMAPK1KMT2APOLB
SCHEMBL12299485 0.83 MAPT (0.56) ALDH1A1MAPTMAPK1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
US-7704312-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2010-04-27 US disclosed
US-7704312-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2010-04-27 US disclosed
US-20080312358-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080312358-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080308004-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080308004-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
WO-2007060264-A2 NON-AQUEOUS PIGMENT DISPERSIONS CONTAINING SPECIFIC DISPERION SYNERGISTS AGFA GRAPHICS NV (BE) 2007-05-31 WO disclosed
EP-1790697-A1 Non-aqueous pigment dispersions containing specific dispersion synergists Agfa Graphics N.V. (BE) 2007-05-30 EP disclosed
EP-1790696-A1 Non-aqueous pigment dispersions containing specific dispersion synergists Agfa Graphics N.V. (BE) 2007-05-30 EP disclosed