SCHEMBL764924

SCHEMBL764924

CC(=O)/C(=N/Nc1ccccc1C(=O)O)C(=O)Nc1ccccc1OCCO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
MAPT P10636 3/20 0.44
MAPK1 P28482 2/20 0.44
KMT2A Q03164 8/20 0.43
PTPN1 P18031 3/20 0.42
MEN1 O00255 5/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
POLB P06746 2/20 0.41
RECQL P46063 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CASP6 P55212 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GAA P10253 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
RBP4 P02753 2/20 0.40
BRD4 O60885 1/20 0.40
FABP3 P05413 1/20 0.40
FABP4 P15090 1/20 0.40
FABP5 Q01469 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL765365 0.88 MAPT (0.55) ALDH1A1MAPTMAPK1KMT2AMEN1
SCHEMBL12998588 0.88 MAPT (0.55) ALDH1A1MAPTMAPK1KMT2AMEN1
SCHEMBL15943552 0.88 MAPT (0.49) ALDH1A1MAPTMAPK1KMT2AMEN1
SCHEMBL15943537 0.87 ALDH1A1 (0.43) ALDH1A1MAPTMAPK1KMT2AMEN1
SCHEMBL12299489 0.86 ALDH1A1 (0.58) ALDH1A1MAPTMAPK1KMT2AMEN1
SCHEMBL10060120 0.86 NPC1 (0.51) ALDH1A1MAPTMAPK1KMT2APTPN1
SCHEMBL13707244 0.85 MAPT (0.47) ALDH1A1MAPTMAPK1KMT2AMEN1
SCHEMBL12299510 0.83 DHODH (0.54) ALDH1A1MAPTMAPK1KMT2AMEN1
SCHEMBL764899 0.81 ALDH1A1 (0.49) ALDH1A1MAPTMAPK1KMT2AMEN1
SCHEMBL764920 0.80 MAPT (0.49) ALDH1A1MAPTMAPK1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904582-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2014-08-13 EP disclosed
EP-1904585-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-10-23 EP disclosed
EP-1904580-B1 PIGMENT DISPERSIONS WITH POYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS AGFA GRAPHICS NV (BE) 2013-10-16 EP disclosed
EP-1904583-B1 PIGMENT DISPERSIONS WITH POLYMERIC DISPERSANTS HAVING PENDING CHROMOPHORE GROUPS. AGFA GRAPHICS NV (BE) 2012-03-21 EP disclosed
US-7582150-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-7582150-B2 Pigment dispersions with polymeric dispersants having pending chromophore groups AGFA GRAPHICS NV (BE) 2009-09-01 US disclosed
US-20080207806-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-08-28 US disclosed
US-20080207806-A1 Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups AGFA GRAPHICS NV (BE) 2008-08-28 US disclosed