SCHEMBL12299595

SCHEMBL12299595

CC(=O)/C(=N/Nc1cccc(C(=O)O)c1)C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.49
ALDH1A1 P00352 5/20 0.46
KMT2A Q03164 5/20 0.44
MEN1 O00255 4/20 0.44
LMNA P02545 1/20 0.44
KDM4E B2RXH2 3/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
PKM P14618 2/20 0.44
GAA P10253 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPK1 P28482 2/20 0.44
TSHR P16473 1/20 0.44
BCL6 P41182 1/20 0.43
BCOR Q6W2J9 1/20 0.43
POLB P06746 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11913348 0.90 MAPT (0.46) MAPTALDH1A1KMT2AMEN1LMNA
SCHEMBL11913350 0.90 MAPT (0.44) MAPTALDH1A1KMT2AMEN1LMNA
SCHEMBL12299494 0.89 MAPT (0.47) MAPTALDH1A1KMT2AMEN1LMNA
SCHEMBL12998478 0.89 MAPT (0.54) MAPTALDH1A1KMT2AMEN1KDM4E
SCHEMBL17126908 0.86 MAPT (0.45) MAPTALDH1A1KMT2AMEN1LMNA
SCHEMBL12299587 0.85 MAPT (0.54) MAPTALDH1A1KMT2AMEN1KDM4E
SCHEMBL13596767 0.85 BCL6 (0.44) MAPTALDH1A1KMT2AMEN1LMNA
SCHEMBL12299528 0.84 BCL6 (0.47) MAPTALDH1A1KMT2AMEN1LMNA
SCHEMBL12299525 0.84 BCL6 (0.49) MAPTALDH1A1KMT2AMEN1LMNA
SCHEMBL12299642 0.84 ALDH1A1 (0.45) MAPTALDH1A1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1790696-B1 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2013-04-10 EP disclosed
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
US-8022117-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2011-09-20 US disclosed
US-7704312-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2010-04-27 US disclosed
US-7704312-B2 Non-aqueous pigment dispersions containing specific dispersion synergists AGFA GRAPHICS NV (BE) 2010-04-27 US disclosed
US-20080312358-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080312358-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080308004-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
US-20080308004-A1 Non-Aqueous Pigment Dispersions Containing Specific Dispersion Synergists AGFA GRAPHICS NV (BE) 2008-12-18 US disclosed
WO-2007060263-A2 NON-AQUEOUS PIGMENT DISPERSIONS CONTAINING SPECIFIC DISPERSION SYNERGISTS AGFA GRAPHICS NV (BE) 2007-05-31 WO disclosed
WO-2007060264-A2 NON-AQUEOUS PIGMENT DISPERSIONS CONTAINING SPECIFIC DISPERION SYNERGISTS AGFA GRAPHICS NV (BE) 2007-05-31 WO disclosed
EP-1790697-A1 Non-aqueous pigment dispersions containing specific dispersion synergists Agfa Graphics N.V. (BE) 2007-05-30 EP disclosed
EP-1790696-A1 Non-aqueous pigment dispersions containing specific dispersion synergists Agfa Graphics N.V. (BE) 2007-05-30 EP disclosed