Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.64 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.64 |
| ▸ | ITGAL | P20701 | 4/20 | 0.64 |
| ▸ | MMP2 | P08253 | 3/20 | 0.57 |
| ▸ | CDK2 | P24941 | 2/20 | 0.56 |
| ▸ | PTPRA | P18433 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PKLR | P30613 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229970 | 1.00 | DNMT1 (0.72) | DNMT1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL5579691 | 0.89 | KMT2A (0.63) | DNMT1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL5579686 | 0.89 | KMT2A (0.63) | DNMT1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL14398100 | 0.88 | ITGB2 (0.61) | DNMT1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL1653793 | 0.83 | KMT2A (0.68) | DNMT1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL13554692 | 0.82 | KMT2A (0.73) | DNMT1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL1333936 | 0.81 | CRHBP (0.56) | KMT2APKM | |
| SCHEMBL1333933 | 0.81 | CRHBP (0.56) | KMT2APKM | |
| SCHEMBL23174994 | 0.80 | KMT2A (0.62) | DNMT1KMT2AITGB2ICAM1ITGAL | |
| SCHEMBL7054118 | 0.79 | ALOX15 (0.64) | KMT2AITGB2ICAM1ITGALMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7881871-B2 | Method for designing surfaces | BIO-LAYER PTY LIMITED (AU) | 2011-02-01 | — | — | US | claimed |
| EP-1700244-A4 | A METHOD FOR DESIGNING SURFACES | BIO LAYER PTY LTD (AU) | 2009-07-08 | — | — | EP | claimed |
| US-20070099235-A1 | Method for designing surfaces | BIO-LAYER PTY LIMITED (AU) | 2007-05-03 | — | — | US | claimed |
| EP-1700244-A1 | A METHOD FOR DESIGNING SURFACES | Bio-Layer Pty Limited (AU) | 2006-09-13 | — | — | EP | claimed |
| WO-2005057462-A1 | A METHOD FOR DESIGNING SURFACES | BIO-LAYER PTY LIMITED (AU) | 2005-06-23 | — | — | WO | claimed |
| US-7881871-B2 | Method for designing surfaces | BIO-LAYER PTY LIMITED (AU) | 2011-02-01 | — | — | US | disclosed |
| EP-1700244-A4 | A METHOD FOR DESIGNING SURFACES | BIO LAYER PTY LTD (AU) | 2009-07-08 | — | — | EP | disclosed |
| EP-1331935-B1 | DERIVATIVES OF TRYPTAMINE AND ANALOGOUS COMPOUNDS, AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | NEURIM PHARMA 1991 (IL) | 2008-10-01 | — | — | EP | disclosed |
| US-20070099235-A1 | Method for designing surfaces | BIO-LAYER PTY LIMITED (AU) | 2007-05-03 | — | — | US | disclosed |
| EP-1700244-A1 | A METHOD FOR DESIGNING SURFACES | Bio-Layer Pty Limited (AU) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005057462-A1 | A METHOD FOR DESIGNING SURFACES | BIO-LAYER PTY LIMITED (AU) | 2005-06-23 | — | — | WO | disclosed |