Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 3/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12303712 | 0.86 | KCNH2 (0.74) | KCNH2CYP2C19CYP3A4CYP2C9DRD1 | |
| SCHEMBL12332796 | 0.83 | KCNH2 (0.68) | KCNH2CYP2C19CYP3A4CYP2C9DRD1 | |
| SCHEMBL12304389 | 0.81 | KCNH2 (0.73) | KCNH2CYP2C19CYP3A4CYP2C9DRD1 | |
| SCHEMBL12303644 | 0.80 | KCNH2 (0.63) | KCNH2CYP2C19CYP3A4CYP2C9DRD1 | |
| SCHEMBL12303641 | 0.80 | KCNH2 (0.72) | KCNH2CYP2C19CYP3A4CYP2C9DRD1 | |
| SCHEMBL12303626 | 0.78 | KCNH2 (0.84) | KCNH2CYP2C19CYP3A4CYP2C9DRD1 | |
| SCHEMBL12303684 | 0.77 | KCNH2 (0.71) | KCNH2CYP2C19CYP3A4CYP2C9DRD1 | |
| SCHEMBL12303616 | 0.77 | KCNH2 (0.84) | KCNH2CYP2C19CYP3A4CYP2C9DRD1 | |
| SCHEMBL12819333 | 0.77 | CYP2C19 (0.64) | KCNH2CYP2C19CYP3A4CYP2C9GRIN1 | |
| SCHEMBL12303781 | 0.77 | CYP2C19 (0.66) | KCNH2CYP2C19CYP3A4CYP2C9NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230465-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) | 2011-09-22 | — | — | US | disclosed |
| US-20110230465-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) | 2011-09-22 | — | — | US | disclosed |
| WO-2011032277-A1 | QUINAZOLINONE DERIVATIVES AS VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230465-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2E | KCNH2 3631/4885CYP2C19 712/4885CYP3A4 745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.