Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492548 | 0.89 | POLB (0.40) | ALDH1A1TDP1POLBCYP1A2GAA | |
| SCHEMBL4848695 | 0.88 | CYP1A2 (0.44) | ALDH1A1TDP1POLBCYP1A2GAA | |
| SCHEMBL3988349 | 0.87 | TDP1 (0.48) | ALDH1A1TDP1POLBCYP1A2GAA | |
| SCHEMBL10535526 | 0.86 | TDP1 (0.47) | ALDH1A1TDP1POLBCYP1A2GAA | |
| SCHEMBL7820981 | 0.85 | ALDH1A1 (0.37) | ALDH1A1TDP1POLBCYP1A2GAA | |
| SCHEMBL16266196 | 0.83 | CYP1A2 (0.49) | ALDH1A1TDP1POLBCYP1A2GAA | |
| SCHEMBL29828109 | 0.83 | CYP1A2 (0.49) | ALDH1A1TDP1POLBCYP1A2GAA | |
| SCHEMBL27951254 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1POLBCYP1A2GAA | |
| SCHEMBL3466829 | 0.80 | TDP1 (0.44) | ALDH1A1TDP1POLBGAASMN1; SMN2 | |
| SCHEMBL12985822 | 0.78 | TSHR (0.40) | ALDH1A1TDP1GAASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10663471-B2 | Fluorescent sensors of peroxynitrite targeted to the endoplasmic reticulum | THE UNIVERSITY OF KANSAS (US) | 2020-05-26 | — | — | US | claimed |
| US-20190310263-A1 | FLUORESCENT SENSORS OF PEROXYNITRITE TARGETED TO THE ENDOPLASMIC RETICULUM | THE UNIVERSITY OF KANSAS | 2019-10-10 | — | — | US | claimed |
| US-7881871-B2 | Method for designing surfaces | BIO-LAYER PTY LIMITED (AU) | 2011-02-01 | — | — | US | claimed |
| EP-1700244-A4 | A METHOD FOR DESIGNING SURFACES | BIO LAYER PTY LTD (AU) | 2009-07-08 | — | — | EP | claimed |
| US-20070099235-A1 | Method for designing surfaces | BIO-LAYER PTY LIMITED (AU) | 2007-05-03 | — | — | US | claimed |
| EP-1700244-A1 | A METHOD FOR DESIGNING SURFACES | Bio-Layer Pty Limited (AU) | 2006-09-13 | — | — | EP | claimed |
| WO-2005057462-A1 | A METHOD FOR DESIGNING SURFACES | BIO-LAYER PTY LIMITED (AU) | 2005-06-23 | — | — | WO | claimed |
| US-10663471-B2 | Fluorescent sensors of peroxynitrite targeted to the endoplasmic reticulum | THE UNIVERSITY OF KANSAS (US) | 2020-05-26 | — | — | US | disclosed |
| US-20190310263-A1 | FLUORESCENT SENSORS OF PEROXYNITRITE TARGETED TO THE ENDOPLASMIC RETICULUM | THE UNIVERSITY OF KANSAS | 2019-10-10 | — | — | US | disclosed |
| US-7881871-B2 | Method for designing surfaces | BIO-LAYER PTY LIMITED (AU) | 2011-02-01 | — | — | US | disclosed |
| EP-1700244-A4 | A METHOD FOR DESIGNING SURFACES | BIO LAYER PTY LTD (AU) | 2009-07-08 | — | — | EP | disclosed |
| US-20070099235-A1 | Method for designing surfaces | BIO-LAYER PTY LIMITED (AU) | 2007-05-03 | — | — | US | disclosed |
| EP-1700244-A1 | A METHOD FOR DESIGNING SURFACES | Bio-Layer Pty Limited (AU) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005057462-A1 | A METHOD FOR DESIGNING SURFACES | BIO-LAYER PTY LIMITED (AU) | 2005-06-23 | — | — | WO | disclosed |
| US-5256395-A | Drug delivery by administering a receptor binding assay having a dual preferential monoclonal antibody conjugating with predetermined haptens | IMMUNOTECH PARTNERS (FR) | 1993-10-26 | — | — | US | disclosed |
| EP-0263046-B1 | AFFINITY ENHANCEMENT IMMUNOLOGICAL REAGENTS FOR DETECTION AND KILLING OF SPECIFIC TARGET CELLS | IMMUNOTECH PARTNERS (FR) | 1992-04-15 | — | — | EP | disclosed |
| EP-0263046-A1 | Affinity enhancement immunological reagents for detection and killing of specific target cells | IMMUNOTECH PARTNERS (FR) | 1988-04-06 | — | — | EP | disclosed |