Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492548 | 0.83 | POLB (0.40) | TDP1POLBGAAALDH1A1MAPT | |
| SCHEMBL1230449 | 0.80 | ALDH1A1 (0.46) | TDP1POLBGAAALDH1A1MAPT | |
| Carbamic Acid SCHEMBL2781218 | 0.74 | POLB (0.39) | TDP1POLBGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL3988349 | 0.70 | TDP1 (0.48) | TDP1POLBGAAALDH1A1MAPT | |
| SCHEMBL2781216 | 0.69 | MAPT (0.40) | TDP1POLBGAAALDH1A1MAPT | |
| SCHEMBL22458880 | 0.69 | POLB (0.52) | POLBALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL4848695 | 0.69 | CYP1A2 (0.44) | TDP1POLBGAAALDH1A1MAPT | |
| SCHEMBL3466064 | 0.68 | TDP1 (0.46) | TDP1POLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7820981 | 0.68 | ALDH1A1 (0.37) | TDP1POLBGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL10535526 | 0.67 | TDP1 (0.47) | TDP1POLBGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071772-A2 | SYNTHESIS OF 3B-AMINO-5-CHOLESTENE AND RELATED 3B-HALIDES INVOLVING I-STEROID AND RETRO-I-STEROID REARRANGEMENTS | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-06-24 | — | — | WO | disclosed |