Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 7/20 | 0.78 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | OGA | O60502 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12307735 | 0.89 | PIK3CG (0.76) | PIK3CGGAASLC27A1ALDH1A1KMT2A | |
| SCHEMBL12307654 | 0.88 | PIK3CG (0.62) | PIK3CGGAASLC27A1ALDH1A1KMT2A | |
| SCHEMBL10085357 | 0.88 | PIK3CG (1.00) | PIK3CGGAAALDH1A1KMT2ARAB9A | |
| SCHEMBL10085362 | 0.86 | PIK3CG (0.76) | PIK3CGALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL10085355 | 0.81 | PIK3CG (0.74) | PIK3CGRAB9ANPC1MAPTCYP1A2 | |
| SCHEMBL10085345 | 0.81 | PIK3CG (0.76) | PIK3CGGAASLC27A1RAB9ANPC1 | |
| SCHEMBL10085359 | 0.80 | PIK3CG (1.00) | PIK3CGALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL10085356 | 0.80 | PIK3CG (1.00) | PIK3CGALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL16888149 | 0.80 | RORC (0.55) | PIK3CGGAASLC27A1ALDH1A1KMT2A | |
| SCHEMBL10085363 | 0.79 | PIK3CG (0.75) | PIK3CGRAB9ANPC1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230472-A1 | RING-FUSED AZOLE DERIVATIVE HAVING PI3K-INHIBITING ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2011-09-22 | — | — | US | disclosed |
| US-20110230472-A1 | RING-FUSED AZOLE DERIVATIVE HAVING PI3K-INHIBITING ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230472-A1 | RING-FUSED AZOLE DERIVATIVE HAVING PI3K-INHIBITING ACTIVITY | PIK3R5, PIK3R4, PIK3R1 | PIK3CG 14/4885GAA 2338/4885SLC27A1 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.