Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 14/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | RORB | Q92753 | 1/20 | 0.52 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16888128 | 0.90 | RORC (0.50) | RORCPIK3CGRORBALDH1A1LMNA | |
| SCHEMBL16888126 | 0.89 | RORC (0.53) | RORCRORBALDH1A1GAAESR1 | |
| SCHEMBL16888130 | 0.88 | RORC (0.50) | RORCRORBALDH1A1LMNAGAA | |
| SCHEMBL16879789 | 0.81 | LMNA (0.73) | RORCRORBALDH1A1LMNAGAA | |
| SCHEMBL12307656 | 0.80 | PIK3CG (0.78) | PIK3CGSLC27A1ALDH1A1LMNAGAA | |
| SCHEMBL16888127 | 0.79 | PIK3CG (0.45) | RORCPIK3CGSLC27A1ALDH1A1GAA | |
| SCHEMBL16888045 | 0.79 | RORC (0.44) | RORCPIK3CGRORBALDH1A1GAA | |
| SCHEMBL19772202 | 0.79 | RORC (0.56) | RORCRORB | |
| SCHEMBL19772097 | 0.79 | RORC (0.56) | RORCRORB | |
| SCHEMBL16888129 | 0.78 | ALDH1A1 (0.44) | RORCPIK3CGRORBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015101928-A1 | FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS ROR GAMMA MODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-07-09 | — | — | WO | disclosed |